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Defensin Beta 2 (DEFB4A) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822334

MBS822334 is an antibody targeting DEFB4A. Also known as Anti-Defensin beta 2 Antibody. Reactive in Human. Host: Rabbit. Rabbit polyclonal antibody to Defensin beta 2 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Defensin beta 2 (DEFB4A), Polyclonal Antibody
Full Product Name
Anti-Defensin beta 2 Antibody
Product Gene Name
Product Synonym Gene Name
DEFB4B
Product Synonym Names
DEFB102; DEFB2; DEFB4; Beta-defensin 4A; Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of Defensin beta 2 protein.
Preparation and Storage
Upon delivery, aliquot and store at -20°C for one year.
Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
OMIM
602215
3D Structure
ModBase 3D Structure for O15263
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Defensin beta 2. The exact sequence is proprietary.
Applications Tested/Suitable for anti-DEFB4A antibody
Western Blot (WB) Immunohistochemical (IHC)
Application Notes for anti-DEFB4A antibody
WB: 1/500 - 1/1000
IHC: 1/50-1/200

Western Blot (WB) of anti-DEFB4A antibody

Western blot analysis of Defensin beta 2 expression in HEK293T (A) whole cell lysates.
Rabbit Anti-DEFB4A Polyclonal Antibody – Cat# MBS822334

Immunohistochemical (IHC) of anti-DEFB4A antibody

Immunohistochemical analysis of Defensin beta 2 staining in human small intestine formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-DEFB4A Polyclonal Antibody, Immunohistochemical (IHC) – Cat# MBS822334

Other Notes

Small volumes of anti-DEFB4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFB4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 4B
NCBI Official Synonym Full Names
defensin, beta 4B
NCBI Official Symbol
DEFB4B
NCBI Official Synonym Symbols
DEFB4P
UniProt Protein Name
Beta-defensin 4A
UniProt Synonym Protein Names
Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1
Protein Family
UniProt Gene Name
DEFB4A
UniProt Synonym Gene Names
DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1
UniProt Entry Name
DFB4A_HUMAN
NCBI Protein Information
beta-defensin 4B; defensin, beta 4, pseudogene

NCBI Summary for DEFB4A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]

UniProt Comments for DEFB4A

defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: Golgi lumen; extracellular region

Biological Process: G-protein coupled receptor protein signaling pathway; defense response to bacterium; innate immune response; immune response; chemotaxis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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