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CD54 (ICAM1) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824491

Sandwich ELISA for quantitative detection of Rat CD54 concentrations. More details

$615 / 96 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD54 (ICAM1), ELISA Kit
Full Product Name
Rat CD54 ELISA Kit
Product Gene Name
ICAM1 elisa kit
Product Synonym Names
Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54
Species Reactivity
Rat
Assay Type
Sandwich
Samples
Cell Culture Supernatants, Serum, Plasma
Detection Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
2 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
60,142 Da
3D Structure
ModBase 3D Structure for Q00238
Detection Method
Colorimetric
Applications Tested/Suitable for ICAM1 elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of ICAM1 elisa kit

Rat ICAM1 ELISA Kit – Cat# MBS824491

Other Notes

Small volumes of ICAM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ICAM1 purchase

MBS824491 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD54 (ICAM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ICAM1. The ELISA analytical biochemical technique of the MBS824491 kit is based on ICAM1 antibody-ICAM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ICAM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ICAM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ICAM1. It may not necessarily be applicable to this product.

NCBI GI #
6981068
NCBI GeneID
25464
NCBI Accession #
NP_037099.1
UniProt Primary Accession #
Q00238
UniProt Related Accession #
Q00238
GenBank Nucleotide #
NM_012967.1
NCBI Official Full Name
intercellular adhesion molecule 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 1
NCBI Official Symbol
Icam1
NCBI Official Synonym Symbols
CD54; ICAM
UniProt Protein Name
Intercellular adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD54
Protein Family
Intercellular adhesion molecule
UniProt Gene Name
Icam1
UniProt Synonym Gene Names
Icam-1; ICAM-1
UniProt Entry Name
ICAM1_RAT
NCBI Protein Information
intercellular adhesion molecule 1; ICAM-1

NCBI Summary for ICAM1

cell adhesion molecule; ligand for leukocyte adhesion molecule LFA-1 [RGD, Feb 2006]

UniProt Comments for ICAM1

ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.

Protein type: Membrane protein, integral; Cell adhesion; Immunoglobulin superfamily

Cellular Component: extracellular space; cell surface; focal adhesion; membrane; integral to plasma membrane; plasma membrane; immunological synapse; lipid raft; external side of plasma membrane

Molecular Function: integrin binding; protein complex binding

Biological Process: positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; response to lipopolysaccharide; response to organic cyclic substance; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; leukocyte adhesion; cellular response to nutrient levels; cell-cell adhesion; sensory perception of sound; ovarian follicle development; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; membrane to membrane docking; response to sulfur dioxide; cell adhesion; acute inflammatory response to antigenic stimulus; response to drug; regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; response to amphetamine; cell aging; response to amino acid stimulus; positive regulation of peptidyl-tyrosine phosphorylation; response to ethanol; response to copper ion; positive regulation of actin filament polymerization; response to hypoxia; positive regulation of vasoconstriction; cell adhesion mediated by integrin; adhesion to host; response to ionizing radiation; leukocyte migration; positive regulation of GTPase activity
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Research Articles on ICAM1

1. Upregulation of the adhesion molecules VCAM-1, ICAM-1, and E-selectin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ICAM1 elisa kit

 Reference Product  PubMed Publications
 Tnf elisa kit  >3320 publications with ICAM1 and Tnf
 Itgb2 elisa kit  >879 publications with ICAM1 and Itgb2
 Ccl2 elisa kit  >675 publications with ICAM1 and Ccl2
 Itgal elisa kit  >472 publications with ICAM1 and Itgal
 Itgam elisa kit  >437 publications with ICAM1 and Itgam
 Cd44 elisa kit  >370 publications with ICAM1 and Cd44
 Nos2 elisa kit  >148 publications with ICAM1 and Nos2
 Il6 elisa kit  >148 publications with ICAM1 and Il6
 Sele elisa kit  >79 publications with ICAM1 and Sele

Pathways associated with ICAM1 elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram

Diseases associated with ICAM1 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5552 publications with ICAM1 and Inflammation
 Necrosis Antibodies  >4742 publications with ICAM1 and Necrosis
 Cardiovascular Diseases Antibodies  >3593 publications with ICAM1 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >1440 publications with ICAM1 and Atherosclerosis
 Reperfusion Injury Antibodies  >875 publications with ICAM1 and Reperfusion Injury
 Myocardial Ischemia Antibodies  >787 publications with ICAM1 and Myocardial Ischemia
 Kidney Diseases Antibodies  >752 publications with ICAM1 and Kidney Diseases
 Liver Diseases Antibodies  >547 publications with ICAM1 and Liver Diseases
 Hypertension Antibodies  >519 publications with ICAM1 and Hypertension
 Asthma Antibodies  >501 publications with ICAM1 and Asthma

Organs/Tissues associated with ICAM1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1753 publications with ICAM1 and Lung
 Liver Antibodies  >1174 publications with ICAM1 and Liver
 Brain Antibodies  >1162 publications with ICAM1 and Brain
 Embryonic Tissue Antibodies  >770 publications with ICAM1 and Embryonic Tissue
 Spleen Antibodies  >365 publications with ICAM1 and Spleen
 Connective Tissue Antibodies  >208 publications with ICAM1 and Connective Tissue
 Placenta Antibodies  >116 publications with ICAM1 and Placenta
 Inner Ear Antibodies  >22 publications with ICAM1 and Inner Ear
 Uncharacterized Tissue Antibodies  >3 publications with ICAM1 and Uncharacterized Tissue
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