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CD106 (VCAM1) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824517

Sandwich ELISA for quantitative detection of Mouse CD106 concentrations. More details

$615 / 96 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD106 (VCAM1), ELISA Kit
Full Product Name
Mouse CD106 ELISA Kit
Product Gene Name
VCAM1 elisa kit
Product Synonym Names
L1CAM; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Cell Culture Supernatants, Serum, Plasma
Detection Range
156 pg/ml - 10000 pg/ml
Sensitivity
5 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
38,372 Da
3D Structure
ModBase 3D Structure for P29533
Detection Method
Colorimetric
Applications Tested/Suitable for VCAM1 elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of VCAM1 elisa kit

Mouse VCAM1 ELISA Kit – Cat# MBS824517

Other Notes

Small volumes of VCAM1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VCAM1 purchase

MBS824517 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD106 (VCAM1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VCAM1. The ELISA analytical biochemical technique of the MBS824517 kit is based on VCAM1 antibody-VCAM1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VCAM1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VCAM1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for VCAM1. It may not necessarily be applicable to this product.

NCBI GI #
170295823
NCBI GeneID
22329
NCBI Accession #
NP_035823.3
UniProt Primary Accession #
P29533
UniProt Related Accession #
P29533
GenBank Nucleotide #
NM_011693.3
NCBI Official Full Name
vascular cell adhesion protein 1
NCBI Official Synonym Full Names
vascular cell adhesion molecule 1
NCBI Official Symbol
Vcam1
NCBI Official Synonym Symbols
CD106; Vcam-1
UniProt Protein Name
Vascular cell adhesion protein 1
UniProt Synonym Protein Names
CD_antigen: CD106
Protein Family
Vascular cell adhesion protein
UniProt Gene Name
Vcam1
UniProt Synonym Gene Names
Vcam-1; V-CAM 1; VCAM-1
UniProt Entry Name
VCAM1_MOUSE
NCBI Protein Information
vascular cell adhesion protein 1; V-CAM 1

UniProt Comments for VCAM1

VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Cellular Component: Golgi apparatus; extracellular space; cell surface; microvillus; endoplasmic reticulum; early endosome; integral to membrane; membrane; apical part of cell; plasma membrane; podosome; sarcolemma; filopodium; external side of plasma membrane

Molecular Function: amine oxidase activity; integrin binding; cell adhesion molecule binding

Biological Process: heterophilic cell adhesion; cell-cell adhesion; leukocyte adhesion; viral reproduction; cell-matrix adhesion; heart development; positive regulation of T cell proliferation; amine metabolic process; leukocyte tethering or rolling; cell adhesion
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Research Articles on VCAM1

1. pretreatment with C66 not only significantly reduced high glucose (HG)-induced over-expressions of VCAM-1, ICAM-1 and MCP-1, but also remarkably inhibited NF-kappaB activation, MAPKs phosphorylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VCAM1 elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram

Diseases associated with VCAM1 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >78 publications with VCAM1 and Inflammation
 Cardiovascular Diseases Antibodies  >52 publications with VCAM1 and Cardiovascular Diseases
 Necrosis Antibodies  >48 publications with VCAM1 and Necrosis
 Atherosclerosis Antibodies  >38 publications with VCAM1 and Atherosclerosis
 Kidney Diseases Antibodies  >13 publications with VCAM1 and Kidney Diseases
 Hypertension Antibodies  >12 publications with VCAM1 and Hypertension
 Heart Diseases Antibodies  >10 publications with VCAM1 and Heart Diseases
 Myocardial Ischemia Antibodies  >9 publications with VCAM1 and Myocardial Ischemia
 Anemia Antibodies  >8 publications with VCAM1 and Anemia
 Fibrosis Antibodies  >7 publications with VCAM1 and Fibrosis

Organs/Tissues associated with VCAM1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >23 publications with VCAM1 and Kidney
 Spleen Antibodies  >6 publications with VCAM1 and Spleen
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