Mouse TNFSF10 ELISA Kit – Cat# MBS824628

CD253 (TNFSF10) ELISA Kit for Mouse

Name: Mouse TNFSF10 ELISA Kit; CD253; MyBioSource
Brand: MyBioSource
SKU: MBS824628
Price: 640 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824628

Sandwich ELISA for quantitative detection of Mouse CD253 concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

CD253 (TNFSF10), ELISA Kit

Full Product Name

Mouse CD253 ELISA Kit

Product Gene Name

TNFSF10 elisa kit

Product Synonym Names

APO2L; TRAIL; Tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD253

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Cell Culture Supernatants, Serum, Plasma

Detection Range

15.6 pg/ml - 1000 pg/ml

Sensitivity

5 pg/ml

Preparation and Storage

Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Molecular Weight

33,477 Da

3D Structure

ModBase 3D Structure for P50592

Detection Method

Colorimetric

Applications Tested/Suitable for TNFSF10 elisa kit

Sandwich ELISA (SE)

Other Notes

Small volumes of TNFSF10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFSF10 purchase

MBS824628 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD253 (TNFSF10) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TNFSF10. The ELISA analytical biochemical technique of the MBS824628 kit is based on TNFSF10 antibody-TNFSF10 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFSF10 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNFSF10. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TNFSF10. It may not necessarily be applicable to this product.

NCBI GI #

6678431

NCBI GeneID

22035

NCBI Accession #

NP_033451.1

UniProt Primary Accession #

P50592

UniProt Related Accession #

P50592

GenBank Nucleotide #

NM_009425.2

NCBI Official Full Name

tumor necrosis factor ligand superfamily member 10

NCBI Official Synonym Full Names

tumor necrosis factor (ligand) superfamily, member 10

NCBI Official Symbol

Tnfsf10

NCBI Official Synonym Symbols

TL2; Ly81; Trail; APO-2L; AI448571; A330042I21Rik

UniProt Protein Name

Tumor necrosis factor ligand superfamily member 10

UniProt Synonym Protein Names

TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253

Protein Family

Tumor necrosis factor ligand superfamily

UniProt Gene Name

Tnfsf10

UniProt Synonym Gene Names

Trail; Protein TRAIL

UniProt Entry Name

TNF10_MOUSE

NCBI Protein Information

tumor necrosis factor ligand superfamily member 10; TRAIL/APO2L; TNF-related apoptosis inducing ligand; TNF-related apoptosis-inducing ligand

UniProt Comments for TNFSF10

TRAIL: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Homotrimer. Widespread; most predominant in spleen, lung and prostate. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cytokine

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor binding

Biological Process: apoptosis; positive regulation of apoptosis; positive regulation of caspase activity; immune response

Research Articles on TNFSF10

1. These results suggest that TRAIL inhibits VEGF-induced angiogenesis by increasing caspase-8 activity and subsequently decreasing non-apoptotic signaling functions of procaspase-8, without inducing caspase-3 activation and endothelial cell cytotoxicity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TNFSF10 elisa kit

Reference Product	PubMed Publications
Tnfrsf10b elisa kit	>2761 publications with TNFSF10 and Tnfrsf10b
Casp8 elisa kit	>1291 publications with TNFSF10 and Casp8
Fadd elisa kit	>630 publications with TNFSF10 and Fadd
Cflar elisa kit	>255 publications with TNFSF10 and Cflar
Tnfrsf11b elisa kit	>172 publications with TNFSF10 and Tnfrsf11b
Ifnar1 elisa kit	>3 publications with TNFSF10 and Ifnar1
Prdx4 elisa kit	>1 publications with TNFSF10 and Prdx4
Tnfrsf23 elisa kit	>1 publications with TNFSF10 and Tnfrsf23
Ifngr1 elisa kit	>1 publications with TNFSF10 and Ifngr1

Pathways associated with TNFSF10 elisa kit

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Signaling Pathway antibodies	Apoptosis Signaling Pathway Diagram
Caspase-8 Activation By Cleavage Pathway antibodies	Caspase-8 Activation By Cleavage Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Death Receptor Signalling Pathway antibodies	Death Receptor Signalling Pathway Diagram
Dimerization Of Procaspase-8 Pathway antibodies	Dimerization Of Procaspase-8 Pathway Diagram

Diseases associated with TNFSF10 elisa kit

Disease Name	Pubmed Publications
Necrosis Antibodies	>3827 publications with TNFSF10 and Necrosis
Leukemia Antibodies	>464 publications with TNFSF10 and Leukemia
Colorectal Neoplasms Antibodies	>342 publications with TNFSF10 and Colorectal Neoplasms
Liver Diseases Antibodies	>336 publications with TNFSF10 and Liver Diseases
Breast Neoplasms Antibodies	>311 publications with TNFSF10 and Breast Neoplasms
Liver Neoplasms Antibodies	>295 publications with TNFSF10 and Liver Neoplasms
Lung Neoplasms Antibodies	>289 publications with TNFSF10 and Lung Neoplasms
Neoplasms, Experimental Antibodies	>281 publications with TNFSF10 and Neoplasms, Experimental
Inflammation Antibodies	>267 publications with TNFSF10 and Inflammation
Glioma Antibodies	>247 publications with TNFSF10 and Glioma

Organs/Tissues associated with TNFSF10 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>459 publications with TNFSF10 and Liver
Lung Antibodies	>388 publications with TNFSF10 and Lung
Kidney Antibodies	>154 publications with TNFSF10 and Kidney
Bone Marrow Antibodies	>112 publications with TNFSF10 and Bone Marrow
Muscle Antibodies	>77 publications with TNFSF10 and Muscle
Spleen Antibodies	>71 publications with TNFSF10 and Spleen
Mixed Antibodies	>31 publications with TNFSF10 and Mixed
Thymus Antibodies	>26 publications with TNFSF10 and Thymus
Spinal Cord Antibodies	>12 publications with TNFSF10 and Spinal Cord
Mammary Gland Antibodies	>7 publications with TNFSF10 and Mammary Gland