PS2 (TFF1) ELISA Kit for Human

Name: Human TFF1 ELISA Kit; PS2; MyBioSource
Brand: MyBioSource
SKU: MBS824936
Price: 640 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824936

Sandwich ELISA for quantitative detection of Human PS2 concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

PS2 (TFF1), ELISA Kit

Full Product Name

Human PS2 ELISA Kit

Product Gene Name

TFF1 elisa kit

Product Synonym Names

BCEI; PS2; Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2

Species Reactivity

Human

Assay Type

Sandwich

Samples

Cell Culture Supernatants, Serum, Plasma

Detection Range

15.6 pg/ml - 1000 pg/ml

Sensitivity

10 pg/ml

Preparation and Storage

Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Molecular Weight

9,150 Da

OMIM

113710

3D Structure

ModBase 3D Structure for P04155

Detection Method

Colorimetric

Applications Tested/Suitable for TFF1 elisa kit

Sandwich ELISA (SE)

Other Notes

Small volumes of TFF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TFF1 purchase

MBS824936 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PS2 (TFF1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TFF1. The ELISA analytical biochemical technique of the MBS824936 kit is based on TFF1 antibody-TFF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TFF1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TFF1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TFF1. It may not necessarily be applicable to this product.

NCBI GI #

4507451

NCBI GeneID

7031

NCBI Accession #

NP_003216.1

UniProt Primary Accession #

P04155

UniProt Related Accession #

P04155

GenBank Nucleotide #

NM_003225.2

NCBI Official Full Name

trefoil factor 1

NCBI Official Synonym Full Names

trefoil factor 1

NCBI Official Symbol

TFF1

NCBI Official Synonym Symbols

pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21

UniProt Protein Name

Trefoil factor 1

UniProt Synonym Protein Names

Breast cancer estrogen-inducible protein; PNR-2; Polypeptide P1.A; hP1.A; Protein pS2

Protein Family

Trefoil factor

UniProt Gene Name

TFF1

UniProt Synonym Gene Names

BCEI; PS2; hP1.A

UniProt Entry Name

TFF1_HUMAN

NCBI Protein Information

trefoil factor 1; protein pS2; polypeptide P1.A; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence

NCBI Summary for TFF1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

UniProt Comments for TFF1

TFF1: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: extracellular space

Molecular Function: protein binding; growth factor activity

Biological Process: response to peptide hormone stimulus; negative regulation of cell proliferation; maintenance of gastrointestinal epithelium; digestion; carbohydrate metabolic process; cell differentiation; response to iron ion; response to estradiol stimulus

Research Articles on TFF1

1. Piezo1 is a novel TFF1 binding protein that is important for TFF1-mediated cell migration in gastric cancer cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TFF1 elisa kit

Reference Product	PubMed Publications
FOXA1 elisa kit	>14 publications with TFF1 and FOXA1
MUC5B elisa kit	>11 publications with TFF1 and MUC5B
ESR1 elisa kit	>9 publications with TFF1 and ESR1
PCNA elisa kit	>7 publications with TFF1 and PCNA
GKN2 elisa kit	>7 publications with TFF1 and GKN2
NCOA1 elisa kit	>3 publications with TFF1 and NCOA1
NCOA3 elisa kit	>3 publications with TFF1 and NCOA3
NCOA2 elisa kit	>2 publications with TFF1 and NCOA2

Pathways associated with TFF1 elisa kit

Products by Pathway	Pathway Diagram
FOXA1 Transcription Factor Network Pathway antibodies	FOXA1 Transcription Factor Network Pathway Diagram
Integrated Pancreatic Cancer Pathway antibodies	Integrated Pancreatic Cancer Pathway Diagram

Diseases associated with TFF1 elisa kit

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>404 publications with TFF1 and Breast Neoplasms
Adenocarcinoma Antibodies	>134 publications with TFF1 and Adenocarcinoma
Neoplasm Metastasis Antibodies	>73 publications with TFF1 and Neoplasm Metastasis
Inflammation Antibodies	>41 publications with TFF1 and Inflammation
Neoplasm Invasiveness Antibodies	>37 publications with TFF1 and Neoplasm Invasiveness
Hyperplasia Antibodies	>34 publications with TFF1 and Hyperplasia
Neoplasms, Experimental Antibodies	>30 publications with TFF1 and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>22 publications with TFF1 and Cell Transformation, Neoplastic
Precancerous Conditions Antibodies	>18 publications with TFF1 and Precancerous Conditions
Lung Neoplasms Antibodies	>17 publications with TFF1 and Lung Neoplasms

Organs/Tissues associated with TFF1 elisa kit

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>184 publications with TFF1 and Stomach
Intestine Antibodies	>80 publications with TFF1 and Intestine
Blood Antibodies	>64 publications with TFF1 and Blood
Prostate Antibodies	>23 publications with TFF1 and Prostate
Pancreas Antibodies	>18 publications with TFF1 and Pancreas
Brain Antibodies	>15 publications with TFF1 and Brain
Mammary Gland Antibodies	>11 publications with TFF1 and Mammary Gland
Ovary Antibodies	>9 publications with TFF1 and Ovary
Uncharacterized Tissue Antibodies	>1 publications with TFF1 and Uncharacterized Tissue