MERTK ELISA Kit for Mouse

Name: Mouse MERTK ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS824954
Price: 640 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824954

Sandwich ELISA for quantitative detection of Mouse MERTK concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

MERTK, ELISA Kit

Full Product Name

Mouse MERTK ELISA Kit

Product Gene Name

MERTK elisa kit

Product Synonym Names

MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Cell Culture Supernatants, Cell lysates, Tissue Homogenates, Serum

Detection Range

78 pg/ml - 5000 pg/ml

Sensitivity

10 pg/ml

Preparation and Storage

Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Molecular Weight

110,157 Da

3D Structure

ModBase 3D Structure for Q60805

Detection Method

Colorimetric

Applications Tested/Suitable for MERTK elisa kit

Sandwich ELISA (SE)

Other Notes

Small volumes of MERTK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MERTK purchase

MBS824954 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MERTK, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MERTK. The ELISA analytical biochemical technique of the MBS824954 kit is based on MERTK antibody-MERTK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MERTK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MERTK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MERTK. It may not necessarily be applicable to this product.

NCBI GI #

7106355

NCBI GeneID

17289

NCBI Accession #

NP_032613.1

UniProt Primary Accession #

Q60805

UniProt Secondary Accession #

Q62194

UniProt Related Accession #

Q60805

GenBank Nucleotide #

NM_008587.1

NCBI Official Full Name

tyrosine-protein kinase Mer

NCBI Official Synonym Full Names

c-mer proto-oncogene tyrosine kinase

NCBI Official Symbol

Mertk

NCBI Official Synonym Symbols

Eyk; Mer; Nyk; nmf12

UniProt Protein Name

Tyrosine-protein kinase Mer

UniProt Synonym Protein Names

Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Protein Family

Tyrosine-protein kinase

UniProt Gene Name

Mertk

UniProt Synonym Gene Names

Mer

UniProt Entry Name

MERTK_MOUSE

NCBI Protein Information

tyrosine-protein kinase Mer; Tyro 12; proto-oncogene c-Mer; receptor tyrosine kinase MerTK; proto-oncogene tyrosine-protein kinase Mer

UniProt Comments for MERTK

Mer: a proto-oncogene receptor tyrosine-protein kinase of the Axl family. Binds several ligands including LGALS3, Tubby, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3

Protein type: Kinase, protein; Oncoprotein; Membrane protein, integral; Protein kinase, tyrosine (receptor); EC 2.7.10.1; Protein kinase, TK; TK group; Axl family

Cellular Component: extracellular space; photoreceptor outer segment; membrane; cell; cytoplasm; integral to membrane; intracellular

Molecular Function: transferase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity

Biological Process: negative regulation of lymphocyte activation; platelet activation; vagina development; protein amino acid phosphorylation; phagocytosis; natural killer cell differentiation; retina development in camera-type eye; positive regulation of phagocytosis; protein kinase B signaling cascade; spermatogenesis; phosphorylation; apoptotic cell clearance; secretion by cell

Research Articles on MERTK

1. Data indicate that MerTK, a receptor kinase, was essential for the engulfment of pyrenocytes by the central macrophages at erythroblastic islands.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MERTK elisa kit

Reference Product	PubMed Publications
Gas6 elisa kit	>72 publications with MERTK and Gas6
Rpe65 elisa kit	>14 publications with MERTK and Rpe65
Crb1 elisa kit	>7 publications with MERTK and Crb1
Tulp1 elisa kit	>7 publications with MERTK and Tulp1
Gucy2d elisa kit	>5 publications with MERTK and Gucy2d
Lrat elisa kit	>5 publications with MERTK and Lrat
Pros1 elisa kit	>3 publications with MERTK and Pros1
Spata7 elisa kit	>1 publications with MERTK and Spata7

Pathways associated with MERTK elisa kit

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram

Diseases associated with MERTK elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>50 publications with MERTK and Inflammation
Retinitis Pigmentosa Antibodies	>40 publications with MERTK and Retinitis Pigmentosa
Disease Models, Animal Antibodies	>37 publications with MERTK and Disease Models, Animal
Nervous System Diseases Antibodies	>26 publications with MERTK and Nervous System Diseases
Necrosis Antibodies	>23 publications with MERTK and Necrosis
Brain Diseases Antibodies	>14 publications with MERTK and Brain Diseases
Nerve Degeneration Antibodies	>10 publications with MERTK and Nerve Degeneration
Lymphoma Antibodies	>10 publications with MERTK and Lymphoma
Thrombosis Antibodies	>10 publications with MERTK and Thrombosis
Cell Transformation, Neoplastic Antibodies	>8 publications with MERTK and Cell Transformation, Neoplastic

Organs/Tissues associated with MERTK elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>30 publications with MERTK and Bone Marrow
Brain Antibodies	>25 publications with MERTK and Brain
Lung Antibodies	>16 publications with MERTK and Lung
Testis Antibodies	>11 publications with MERTK and Testis
Liver Antibodies	>9 publications with MERTK and Liver
Kidney Antibodies	>7 publications with MERTK and Kidney
Embryonic Tissue Antibodies	>6 publications with MERTK and Embryonic Tissue
Skin Antibodies	>4 publications with MERTK and Skin
Mammary Gland Antibodies	>3 publications with MERTK and Mammary Gland
Heart Antibodies	>3 publications with MERTK and Heart