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CXCL2 ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS825015

Sandwich ELISA for quantitative detection of Rat CXCL2 concentrations. More details

$615 / 96 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CXCL2, ELISA Kit
Full Product Name
Rat CXCL2 ELISA Kit
Product Gene Name
CXCL2 elisa kit
Product Synonym Names
GRO2; GROB; MIP2A; SCYB2; C-X-C motif chemokine 2; Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha
Species Reactivity
Rat
Assay Type
Sandwich
Samples
Cell Culture Supernatants, Serum, Plasma
Detection Range
15.6 pg/ml - 1000 pg/ml
Sensitivity
10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
10,783 Da
3D Structure
ModBase 3D Structure for P30348
Detection Method
Colorimetric
Applications Tested/Suitable for CXCL2 elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of CXCL2 elisa kit

Rat CXCL2 ELISA Kit – Cat# MBS825015

Other Notes

Small volumes of CXCL2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL2 purchase

MBS825015 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CXCL2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCL2. The ELISA analytical biochemical technique of the MBS825015 kit is based on CXCL2 antibody-CXCL2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCL2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCL2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL2. It may not necessarily be applicable to this product.

NCBI GI #
16758460
NCBI GeneID
114105
NCBI Accession #
NP_446099.1
UniProt Primary Accession #
P30348
UniProt Secondary Accession #
Q5WA60
UniProt Related Accession #
P30348
GenBank Nucleotide #
NM_053647.1
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 2
NCBI Official Symbol
Cxcl2
NCBI Official Synonym Symbols
Mip-2; Scyb2
UniProt Protein Name
C-X-C motif chemokine 2
UniProt Synonym Protein Names
Cytokine-induced neutrophil chemoattractant 3; CINC-3; Macrophage inflammatory protein 2; MIP2
Protein Family
C-X-C motif chemokine
UniProt Gene Name
Cxcl2
UniProt Synonym Gene Names
Cinc3; Mip-2; Mip2; Scyb2; CINC-3; MIP2
UniProt Entry Name
CXCL2_RAT
NCBI Protein Information
C-X-C motif chemokine 2; MIP2; CINC-3; macrophage inflammatory protein 2; small inducible cytokine subfamily, member 2; cytokine-induced neutrophil chemoattractant 3

NCBI Summary for CXCL2

chemokine involved in the pulmonary inflammatory response [RGD, Feb 2006]

UniProt Comments for CXCL2

CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Cellular Component: extracellular space

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: neutrophil chemotaxis; wound healing; leukocyte chemotaxis; response to amphetamine; response to glucocorticoid stimulus; positive regulation of leukocyte chemotaxis; response to estradiol stimulus; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to heat; response to molecule of bacterial origin; response to gamma radiation; immune response; inflammatory response
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Research Articles on CXCL2

1. IL-1beta-mediated regulation of the CXCL1 and CXCL2 genes in pancreatic beta-cells requires stimulus-induced changes in histone chemical modifications, recruitment of the NF-kappaB and STAT1 transcription factors to genomic regulatory sequences within the proximal gene promoters, and increases in phosphorylated forms of RNA polymerase II.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CXCL2 elisa kit

 Reference Product  PubMed Publications
 Cxcl1 elisa kit  >557 publications with CXCL2 and Cxcl1
 Ccl2 elisa kit  >373 publications with CXCL2 and Ccl2
 Il8rb elisa kit  >117 publications with CXCL2 and Il8rb
 Cxcl3 elisa kit  >99 publications with CXCL2 and Cxcl3
 Cxcr4 elisa kit  >44 publications with CXCL2 and Cxcr4
 Ccr2 elisa kit  >42 publications with CXCL2 and Ccr2
 Cxcl6 elisa kit  >36 publications with CXCL2 and Cxcl6
 Ccr1 elisa kit  >25 publications with CXCL2 and Ccr1
 Cxcr3 elisa kit  >18 publications with CXCL2 and Cxcr3
 Ppbp elisa kit  >3 publications with CXCL2 and Ppbp

Pathways associated with CXCL2 elisa kit

 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 PI3K_AKT_NFKB Pathway antibodies  PI3K_AKT_NFKB Pathway Diagram

Diseases associated with CXCL2 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1008 publications with CXCL2 and Inflammation
 Necrosis Antibodies  >643 publications with CXCL2 and Necrosis
 Lung Diseases Antibodies  >383 publications with CXCL2 and Lung Diseases
 Disease Models, Animal Antibodies  >355 publications with CXCL2 and Disease Models, Animal
 Lung Injury Antibodies  >259 publications with CXCL2 and Lung Injury
 Pneumonia Antibodies  >173 publications with CXCL2 and Pneumonia
 Reperfusion Injury Antibodies  >115 publications with CXCL2 and Reperfusion Injury
 Wounds and Injuries Antibodies  >95 publications with CXCL2 and Wounds and Injuries
 Edema Antibodies  >92 publications with CXCL2 and Edema
 Skin Diseases Antibodies  >81 publications with CXCL2 and Skin Diseases

Organs/Tissues associated with CXCL2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >624 publications with CXCL2 and Lung
 Connective Tissue Antibodies  >28 publications with CXCL2 and Connective Tissue
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