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PDGF-Ab (PDGFA) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS825029

Sandwich ELISA for quantitative detection of Mouse PDGF-AB concentrations. More details

$640 / 96 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDGF-AB (PDGFA), ELISA Kit
Full Product Name
Mouse PDGF-AB ELISA Kit
Product Gene Name
PDGFA elisa kit
Product Synonym Gene Name
PDGFB
Product Synonym Names
PDGF1; Platelet-derived growth factor subunit A; PDGF subunit A; PDGF-1; Platelet-derived growth factor A chain; Platelet-derived growth factor alpha polypeptide; PDGF2; SIS; Platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-Sis; Becaplermin
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Cell Culture Supernatants, Serum, Plasma
Detection Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
3 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
22,267 Da
3D Structure
ModBase 3D Structure for P20033
Detection Method
Colorimetric
Applications Tested/Suitable for PDGFA elisa kit
Sandwich ELISA (SE)

Typical Testing Data/Standard Curve (for reference only) of PDGFA elisa kit

Mouse PDGFA ELISA Kit – Cat# MBS825029

Other Notes

Small volumes of PDGFA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDGFA purchase

MBS825029 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PDGF-AB (PDGFA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDGFA. The ELISA analytical biochemical technique of the MBS825029 kit is based on PDGFA antibody-PDGFA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDGFA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDGFA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PDGFA. It may not necessarily be applicable to this product.

NCBI GI #
6715566
NCBI GeneID
18590
NCBI Accession #
NP_032834.1
UniProt Primary Accession #
P20033
UniProt Secondary Accession #
P31240
UniProt Related Accession #
P20033
GenBank Nucleotide #
NM_008808.3
NCBI Official Full Name
platelet-derived growth factor subunit A
NCBI Official Synonym Full Names
platelet derived growth factor, alpha
NCBI Official Symbol
Pdgfa
UniProt Protein Name
Platelet-derived growth factor subunit A
UniProt Synonym Protein Names
PDGF-1; Platelet-derived growth factor A chain; Platelet-derived growth factor alpha polypeptide
Protein Family
Platelet-derived growth factor
UniProt Gene Name
Pdgfa
UniProt Synonym Gene Names
PDGF subunit A
UniProt Entry Name
PDGFA_MOUSE
NCBI Protein Information
platelet-derived growth factor subunit A; PDGF-1; PDGF subunit A; platelet-derived growth factor A chain; platelet-derived growth factor alpha polypeptide

UniProt Comments for PDGFA

PDGFA: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Secreted; Cytokine; Secreted, signal peptide

Cellular Component: extracellular space; cell surface; microvillus; membrane; extracellular region

Molecular Function: collagen binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding

Biological Process: skin development; multicellular organismal development; negative chemotaxis; platelet-derived growth factor receptor signaling pathway; cell projection biogenesis; positive regulation of MAP kinase activity; positive regulation of fibroblast proliferation; regulation of smooth muscle cell migration; positive regulation of MAPKKK cascade; hair follicle development; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; response to wounding; angiogenesis; regulation of peptidyl-tyrosine phosphorylation; negative regulation of phosphatidylinositol biosynthetic process; positive regulation of protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; organ morphogenesis; gut development; positive regulation of cell division; actin cytoskeleton organization and biogenesis; blood coagulation; alveolus development; positive regulation of DNA replication; positive regulation of cell migration
Show more

Research Articles on PDGFA

1. Platelet-derived growth factor plays an integral role in mediating TGF-beta1-dependent mesenchymal stem cell stiffening.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PDGFA elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram

Diseases associated with PDGFA elisa kit

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >23 publications with PDGFA and Carcinoma
 Adenocarcinoma Antibodies  >15 publications with PDGFA and Adenocarcinoma
 Inflammation Antibodies  >10 publications with PDGFA and Inflammation
 Fibrosis Antibodies  >9 publications with PDGFA and Fibrosis
 Disease Models, Animal Antibodies  >8 publications with PDGFA and Disease Models, Animal
 Brain Diseases Antibodies  >7 publications with PDGFA and Brain Diseases
 Neoplasms, Experimental Antibodies  >7 publications with PDGFA and Neoplasms, Experimental
 Cell Transformation, Neoplastic Antibodies  >6 publications with PDGFA and Cell Transformation, Neoplastic
 Mesothelioma Antibodies  >4 publications with PDGFA and Mesothelioma
 Pancreatic Neoplasms Antibodies  >4 publications with PDGFA and Pancreatic Neoplasms

Organs/Tissues associated with PDGFA elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with PDGFA and Lung
 Brain Antibodies  >10 publications with PDGFA and Brain
 Embryonic Tissue Antibodies  >9 publications with PDGFA and Embryonic Tissue
 Kidney Antibodies  >6 publications with PDGFA and Kidney
 Testis Antibodies  >5 publications with PDGFA and Testis
 Ovary Antibodies  >5 publications with PDGFA and Ovary
 Skin Antibodies  >4 publications with PDGFA and Skin
 Heart Antibodies  >4 publications with PDGFA and Heart
 Intestine Antibodies  >3 publications with PDGFA and Intestine
 Prostate Antibodies  >2 publications with PDGFA and Prostate
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