CCL12 ELISA Kit for Mouse

Name: Mouse CCL12 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS825064
Price: 615 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS825064

Sandwich ELISA for quantitative detection of Mouse CCL12 concentrations. More details

$615 / 96 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

CCL12, ELISA Kit

Full Product Name

Mouse CCL12 ELISA Kit

Product Gene Name

CCL12 elisa kit

Product Synonym Names

Mcp5; Scya12; C-C motif chemokine 12; MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; MCP-5; Small-inducible cytokine A12

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Cell Culture Supernatants, Serum, Plasma

Detection Range

31.2 pg/ml - 2000 pg/ml

Sensitivity

10 pg/ml

Preparation and Storage

Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Molecular Weight

11,659 Da

3D Structure

ModBase 3D Structure for Q62401

Detection Method

Colorimetric

Applications Tested/Suitable for CCL12 elisa kit

Sandwich ELISA (SE)

Other Notes

Small volumes of CCL12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL12 purchase

MBS825064 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CCL12, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CCL12. The ELISA analytical biochemical technique of the MBS825064 kit is based on CCL12 antibody-CCL12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CCL12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CCL12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CCL12. It may not necessarily be applicable to this product.

NCBI GI #

119226206

NCBI GeneID

20293

NCBI Accession #

NP_035461.2

UniProt Primary Accession #

Q62401

UniProt Secondary Accession #

Q9QYD6

UniProt Related Accession #

Q62401

GenBank Nucleotide #

NM_011331.2

NCBI Official Full Name

C-C motif chemokine 12

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 12

NCBI Official Symbol

Ccl12

NCBI Official Synonym Symbols

MCP-5; Scya12

UniProt Protein Name

C-C motif chemokine 12

UniProt Synonym Protein Names

MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; MCP-5; Small-inducible cytokine A12

Protein Family

C-C motif chemokine

UniProt Gene Name

Ccl12

UniProt Synonym Gene Names

Mcp5; Scya12; MCP-5

UniProt Entry Name

CCL12_MOUSE

NCBI Protein Information

C-C motif chemokine 12; MCP-1-related chemokine; small inducible cytokine A12; small-inducible cytokine A12; monocyte chemotactic protein 5; monocyte chemoattractant protein 5

UniProt Comments for CCL12

CCL2: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Chemokine

Cellular Component: extracellular space; extracellular region; intracellular

Molecular Function: CCR2 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway; positive regulation of leukocyte migration; MAPKKK cascade; cytoskeleton organization and biogenesis; chemotaxis; macrophage chemotaxis; monocyte chemotaxis; regulation of cell shape; protein kinase B signaling cascade; lipopolysaccharide-mediated signaling pathway; immune response; negative regulation of neuron apoptosis; angiogenesis; inflammatory response; astrocyte cell migration

Research Articles on CCL12

1. After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CCL12 elisa kit

Products by Pathway	Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram

Diseases associated with CCL12 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>33 publications with CCL12 and Inflammation
Disease Models, Animal Antibodies	>22 publications with CCL12 and Disease Models, Animal
Respiratory Tract Diseases Antibodies	>15 publications with CCL12 and Respiratory Tract Diseases
Lung Diseases Antibodies	>14 publications with CCL12 and Lung Diseases
Fibrosis Antibodies	>12 publications with CCL12 and Fibrosis
Necrosis Antibodies	>10 publications with CCL12 and Necrosis
Hypersensitivity Antibodies	>9 publications with CCL12 and Hypersensitivity
Autoimmune Diseases Antibodies	>8 publications with CCL12 and Autoimmune Diseases
Pulmonary Fibrosis Antibodies	>8 publications with CCL12 and Pulmonary Fibrosis
Neoplasms, Experimental Antibodies	>5 publications with CCL12 and Neoplasms, Experimental

Organs/Tissues associated with CCL12 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>13 publications with CCL12 and Brain
Spleen Antibodies	>5 publications with CCL12 and Spleen
Thymus Antibodies	>4 publications with CCL12 and Thymus
Embryonic Tissue Antibodies	>2 publications with CCL12 and Embryonic Tissue
Prostate Antibodies	>2 publications with CCL12 and Prostate