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SRSF7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS827952

MBS827952 is an antibody targeting SRSF7. Reactive in Human, Mouse, Rat, Bovine. Host: Rabbit. Rabbit polyclonal antibody to SRSF7 More details

$225 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRSF7, Polyclonal Antibody
Full Product Name
Anti-SRSF7 Antibody
Product Gene Name
anti-SRSF7 antibody
Product Synonym Names
SFRS7; Serine/arginine-rich splicing factor 7; Splicing factor 9G8; Splicing factor, arginine/serine-rich 7
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SRSF7 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Antibody/Peptide Pairs
SRSF7 peptide (MBS8236100) is used for blocking the activity of SRSF7 antibody (MBS827952)
Molecular Weight
26,012 Da
OMIM
600572
3D Structure
ModBase 3D Structure for Q16629
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SRSF7. The exact sequence is proprietary.
Applications Tested/Suitable for anti-SRSF7 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SRSF7 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Western Blot (WB) of anti-SRSF7 antibody

Western blot analysis of SRSF7 expression in HeLa (A) whole cell lysates.
Rabbit Anti-SRSF7 Polyclonal Antibody – Cat# MBS827952

Immunohistochemistry (IHC) of anti-SRSF7 antibody

Immunohistochemical analysis of SRSF7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit Anti-SRSF7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS827952

Other Notes

Small volumes of anti-SRSF7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SRSF7. It may not necessarily be applicable to this product.

NCBI GI #
72534660
NCBI GeneID
6432
NCBI Accession #
NP_001026854.1
UniProt Primary Accession #
Q16629
UniProt Secondary Accession #
Q564D3; B4DLU6; G5E9M3
UniProt Related Accession #
Q16629
GenBank Nucleotide #
NM_001031684.2
NCBI Official Full Name
serine/arginine-rich splicing factor 7 isoform 1
NCBI Official Synonym Full Names
serine/arginine-rich splicing factor 7
NCBI Official Symbol
SRSF7
NCBI Official Synonym Symbols
9G8; AAG3; SFRS7
UniProt Protein Name
Serine/arginine-rich splicing factor 7
UniProt Synonym Protein Names
Splicing factor 9G8; Splicing factor, arginine/serine-rich 7
Protein Family
Serine/arginine-rich splicing factor
UniProt Gene Name
SRSF7
UniProt Synonym Gene Names
SFRS7
UniProt Entry Name
SRSF7_HUMAN
NCBI Protein Information
serine/arginine-rich splicing factor 7

NCBI Summary for SRSF7

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
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UniProt Comments for SRSF7

SFRS7: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. Belongs to the splicing factor SR family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Spliceosome; RNA splicing

Chromosomal Location of Human Ortholog: 2p22.1

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; zinc ion binding; nucleotide binding

Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; negative regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription
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Research Articles on SRSF7

1. Genome-wide identification of CD95 antigen alternative splicing regulators, such as SRSF7, reveals links with iron homeostasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SRSF7 antibody

 Reference Product  PubMed Publications
 HNRNPA1 antibody  >2 publications with SRSF7 and HNRNPA1
 SRSF5 antibody  >2 publications with SRSF7 and SRSF5
 SRSF11 antibody  >1 publications with SRSF7 and SRSF11

Pathways associated with anti-SRSF7 antibody

 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Transport Of Mature Transcript To Cytoplasm Pathway antibodies  Transport Of Mature Transcript To Cytoplasm Pathway Diagram

Organs/Tissues associated with anti-SRSF7 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with SRSF7 and Blood
 Lung Antibodies  >1 publications with SRSF7 and Lung
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