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DTYMK Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS830778

MBS830778 is an antibody targeting DTYMK. Also known as DTYMK antibody. Host: Mouse. Mouse monoclonal DTYMK antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DTYMK, Monoclonal Antibody
Full Product Name
DTYMK antibody
Product Gene Name
anti-DTYMK antibody
Product Synonym Names
Monoclonal DTYMK; Anti-DTYMK; Deoxythymidylate Kinase; Thymidylate Kinase; CDC8; TMPK; TYMK; dTMP kinase; FLJ44192; PP3731
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1 E6
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
DTYMK antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
21,064 Da
OMIM
188345
3D Structure
ModBase 3D Structure for P23919
Cross-Reactivity
Human
Immunogen
DTYMK antibody was raised in mouse using a full length recombinant protein of human DTYMK (NP_036277) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-DTYMK antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-DTYMK antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-DTYMK antibody
IF: 1:100
WB: 1:2000

Western Blot (WB) of anti-DTYMK antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant DTYMK protein (Right) or empty vector (Left) detected with DTYMK antibody
Mouse Anti-DTYMK Monoclonal Antibody – Cat# MBS830778

Other Notes

Small volumes of anti-DTYMK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DTYMK. It may not necessarily be applicable to this product.

NCBI GI #
42544174
NCBI GeneID
1841
NCBI Accession #
NP_036277
UniProt Primary Accession #
P23919
UniProt Secondary Accession #
Q6FGX1; Q9BUX4; B7ZW70
UniProt Related Accession #
P23919
GenBank Nucleotide #
NM_012145.3
NCBI Official Full Name
thymidylate kinase isoform 1
NCBI Official Synonym Full Names
deoxythymidylate kinase (thymidylate kinase)
NCBI Official Symbol
DTYMK
NCBI Official Synonym Symbols
CDC8; TMPK; TYMK; PP3731
UniProt Protein Name
Thymidylate kinase
UniProt Synonym Protein Names
dTMP kinase
UniProt Gene Name
DTYMK
UniProt Synonym Gene Names
CDC8; TMPK; TYMK
UniProt Entry Name
KTHY_HUMAN
NCBI Protein Information
thymidylate kinase

UniProt Comments for DTYMK

DTYMK: Catalyzes the conversion of dTMP to dTDP. Belongs to the thymidylate kinase family.

Protein type: EC 2.7.4.9; Mitochondrial; Kinase, other; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial intermembrane space; nucleus; cytosol

Molecular Function: uridylate kinase activity; thymidylate kinase activity; nucleoside phosphate kinase activity; ATP binding

Biological Process: myoblast differentiation; cell proliferation; response to cadmium ion; dUDP biosynthetic process; response to estrogen stimulus; nucleobase, nucleoside and nucleotide interconversion; nucleoside monophosphate phosphorylation; nucleobase, nucleoside and nucleotide metabolic process; dTDP biosynthetic process; dTTP biosynthetic process; cell cycle; nucleotide phosphorylation
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Research Articles on DTYMK

1. Lentiviral delivery of small hairpin RNA targeting TMPK in combination with a low dose of doxorubicin as a new approach to kill colon cancer cells regardless of p53 status.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DTYMK antibody

 Reference Product  PubMed Publications
 TYMS antibody  >2 publications with DTYMK and TYMS
 RRM1 antibody  >1 publications with DTYMK and RRM1
 NME1 antibody  >1 publications with DTYMK and NME1
 DUT antibody  >1 publications with DTYMK and DUT

Pathways associated with anti-DTYMK antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
 Pyrimidine Deoxyribonucleotide Phosphorylation Pathway antibodies  Pyrimidine Deoxyribonucleotide Phosphorylation Pathway Diagram
 Pyrimidine Deoxyribonucleotide Phosphorylation Pathway antibodies  Pyrimidine Deoxyribonucleotide Phosphorylation Pathway Diagram
 Pyrimidine Deoxyribonucleotides Biosynthesis From CTP Pathway antibodies  Pyrimidine Deoxyribonucleotides Biosynthesis From CTP Pathway Diagram
 Pyrimidine Deoxyribonucleotides Biosynthesis From CTP Pathway antibodies  Pyrimidine Deoxyribonucleotides Biosynthesis From CTP Pathway Diagram

Diseases associated with anti-DTYMK antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >1 publications with DTYMK and Neoplasm Metastasis
 Carcinoma, Hepatocellular Antibodies  >1 publications with DTYMK and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with DTYMK and Liver Diseases
 Lung Neoplasms Antibodies  >1 publications with DTYMK and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with DTYMK and Liver Neoplasms

Organs/Tissues associated with anti-DTYMK antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with DTYMK and Liver
 Blood Antibodies  >1 publications with DTYMK and Blood
 Lung Antibodies  >1 publications with DTYMK and Lung
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