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STYK1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS831125

MBS831125 is an antibody targeting STYK1. Also known as STYK1 antibody. Host: Mouse. Mouse monoclonal STYK1 antibody More details

$1205 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STYK1, Monoclonal Antibody
Full Product Name
STYK1 antibody
Product Gene Name
anti-STYK1 antibody
Product Synonym Names
Monoclonal STYK1; Anti-STYK1; DKFZp761P1010; STYK1; STYK 1; NOK; Serine/Threonine/Tyrosine Kinase 1; STYK-1; SuRTK106
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2H2F10
Host
Mouse
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
38,585 Da
3D Structure
ModBase 3D Structure for Q6J9G1
Cross-Reactivity
Human
Immunogen
STYK1 antibody was raised in Mouse using a purified recombinant fragment of STYK1 expressed in E Coli as the immunogen.

Product Categories/Family for anti-STYK1 antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-STYK1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-STYK1 antibody
IHC: 1:200-1:1000
WB: 1:500-1:2000

Western Blot (WB) of anti-STYK1 antibody

Western Blot showing STYK1 antibody used against truncated STYK1 recombinant protein (1) and STYK1 (aa47-422)-hIgGFc transfected CHO-K1 cell lysate (2).
Mouse Anti-STYK1 Monoclonal Antibody – Cat# MBS831125

Immunohistochemistry (IHC) of anti-STYK1 antibody

Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), normal cerebrum tissues (B), breast infiltrating carcinoma (C) and breast infiltrating carcinoma (D), showing cytoplasmic localization using STYK1/NOK antibody with DAB staining.
Mouse Anti-STYK1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS831125

Other Notes

Small volumes of anti-STYK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STYK1. It may not necessarily be applicable to this product.

NCBI GI #
148688937
NCBI GeneID
243659
NCBI Accession #
EDL20884.1
UniProt Primary Accession #
Q6J9G1
UniProt Secondary Accession #
Q8BZH6; Q8BZT1
UniProt Related Accession #
Q6J9G1
NCBI Official Full Name
serine/threonine/tyrosine kinase 1
NCBI Official Synonym Full Names
serine/threonine/tyrosine kinase 1
NCBI Official Symbol
Styk1
NCBI Official Synonym Symbols
Nok; AI326477; 9130025L13
UniProt Protein Name
Tyrosine-protein kinase STYK1
UniProt Synonym Protein Names
Novel oncogene with kinase domain; mNOK; Serine/threonine/tyrosine kinase 1
Protein Family
Tyrosine-protein kinase
UniProt Gene Name
Styk1
UniProt Synonym Gene Names
Nok; mNOK
UniProt Entry Name
STYK1_MOUSE
NCBI Protein Information
tyrosine-protein kinase STYK1

UniProt Comments for STYK1

STYK1: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. Belongs to the protein kinase superfamily. Tyr protein kinase family.

Protein type: Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); EC 2.7.10.2; Membrane protein, integral; Oncoprotein; TK group; TK-Unique family

Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; integral to membrane

Molecular Function: transferase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; kinase activity; ATP binding; protein kinase activity

Biological Process: innate immune response; cell differentiation; phosphorylation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation
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Research Articles on STYK1

1. Point mutations at either Y327 or Y356 dramatically blocked cellular transformation by NOK as examined by colony formation and cellular DNA synthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-STYK1 antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram

Diseases associated with anti-STYK1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with STYK1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >2 publications with STYK1 and Lung Neoplasms

Organs/Tissues associated with anti-STYK1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with STYK1 and Lung
 Blood Antibodies  >1 publications with STYK1 and Blood
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