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BIN3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS831743

MBS831743 is an antibody targeting BIN3. Also known as BIN3 antibody. Host: Mouse. Mouse monoclonal BIN3 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BIN3, Monoclonal Antibody
Full Product Name
BIN3 antibody
Product Gene Name
Product Synonym Names
Monoclonal BIN3; Anti-BIN3; Bridging integrator 3; MGC14978; BIN3; BIN 3; BIN-3
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7D6
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
BIN3 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
23,218 Da
OMIM
606396
3D Structure
ModBase 3D Structure for Q9NQY0
Cross-Reactivity
Human
Immunogen
BIN3 antibody was raised in mouse using a full length recombinant protein of human BIN3 (NP_061158) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-BIN3 antibody

Applications Tested/Suitable for anti-BIN3 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-BIN3 antibody
FC: 1:100
IF: 1:100
WB: 1:2000

Western Blot (WB) of anti-BIN3 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant BIN3 protein (Right) or empty vector (Left) detected with BIN3 antibody
Mouse Anti-BIN3 Monoclonal Antibody – Cat# MBS831743

Immunofluorescence (IF) of anti-BIN3 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant BIN3 protein using BIN3 antibody
Mouse Anti-BIN3 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS831743

Other Notes

Small volumes of anti-BIN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BIN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bridging integrator 3
NCBI Official Synonym Full Names
bridging integrator 3
NCBI Official Symbol
BIN3
UniProt Protein Name
Bridging integrator 3
Protein Family
UniProt Gene Name
BIN3
UniProt Entry Name
BIN3_HUMAN
NCBI Protein Information
bridging integrator 3

NCBI Summary for BIN3

The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008]
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UniProt Comments for BIN3

BIN3: Involved in cytokinesis and septation where it has a role in the localization of F-actin. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: cytoplasm; actin filament

Molecular Function: protein binding; cytoskeletal adaptor activity

Biological Process: barrier septum formation; unidimensional cell growth; protein localization; cytokinesis; skeletal muscle fiber development; actin filament organization; myoblast migration involved in skeletal muscle regeneration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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