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MRI1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS832078

MBS832078 is an antibody targeting MRI1. Also known as MRI1 antibody. Host: Mouse. Mouse monoclonal MRI1 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MRI1, Monoclonal Antibody
Full Product Name
MRI1 antibody
Product Gene Name
anti-MRI1 antibody
Product Synonym Names
Monoclonal MRI1; Anti-MRI1; Methylthioribose-1-phosphate isomerase homolog; MGC3207; MTNA; Ypr118w; Mediator of RhoA-dependent invasion; MTR 1 P isomerase; MRI1; MRI 1; MRI-1
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9H7
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
MRI1 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
34,529 Da
OMIM
615105
3D Structure
ModBase 3D Structure for Q9BV20
Cross-Reactivity
Human
Immunogen
MRI1 antibody was raised in mouse using a full length recombinant protein of human MRI1 (NP_115661) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-MRI1 antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-MRI1 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-MRI1 antibody
FC: 1:100
IF: 1:100
IHC: 1:50
WB: 1:2000

Western Blot (WB) of anti-MRI1 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MRI1 protein (Right) or empty vector (Left) detected with MRI1 antibody
Mouse Anti-MRI1 Monoclonal Antibody – Cat# MBS832078

Immunohistochemistry (IHC) of anti-MRI1 antibody

Immunohistochemical analysis of MRI1 protein in paraffin embedded Carcinoma of Human kidney tissue using MRI1 antibody
Mouse Anti-MRI1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS832078

Immunofluorescence (IF) of anti-MRI1 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant MRI1 protein using MRI1 antibody
Mouse Anti-MRI1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS832078

Other Notes

Small volumes of anti-MRI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRI1. It may not necessarily be applicable to this product.

NCBI GI #
23943880
NCBI GeneID
84245
NCBI Accession #
NP_115661
UniProt Primary Accession #
Q9BV20
UniProt Secondary Accession #
Q8NDC9
UniProt Related Accession #
Q9BV20
GenBank Nucleotide #
NM_032285.2
NCBI Official Full Name
methylthioribose-1-phosphate isomerase isoform 2
NCBI Official Synonym Full Names
methylthioribose-1-phosphate isomerase 1
NCBI Official Symbol
MRI1
NCBI Official Synonym Symbols
MRDI; MTNA; Ypr118w
UniProt Protein Name
Methylthioribose-1-phosphate isomerase
UniProt Synonym Protein Names
Mediator of RhoA-dependent invasion; S-methyl-5-thioribose-1-phosphate isomerase
Protein Family
Methylthioribose-1-phosphate isomerase
UniProt Gene Name
MRI1
UniProt Synonym Gene Names
M1Pi; MTR-1-P isomerase
UniProt Entry Name
MTNA_HUMAN
NCBI Protein Information
methylthioribose-1-phosphate isomerase

UniProt Comments for MRI1

MRI1: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Isomerase; EC 5.3.1.23

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: cell projection; cytoplasm; nucleolus; cytosol

Molecular Function: identical protein binding; S-methyl-5-thioribose-1-phosphate isomerase activity

Biological Process: methionine salvage; sulfur amino acid metabolic process; methionine biosynthetic process from S-adenosylmethionine; polyamine metabolic process
Show more

Research Articles on MRI1

1. Data indicate that the structural elements in MRDI distal from the MTR-1-P catalytic site are responsible for the invasion phenotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MRI1 antibody

 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway antibodies  S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway Diagram

Diseases associated with anti-MRI1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with MRI1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >4 publications with MRI1 and Cardiovascular Diseases
 Immune System Diseases Antibodies  >2 publications with MRI1 and Immune System Diseases
 Breast Neoplasms Antibodies  >2 publications with MRI1 and Breast Neoplasms
 Genital Diseases, Male Antibodies  >1 publications with MRI1 and Genital Diseases, Male
 Pancreatic Neoplasms Antibodies  >1 publications with MRI1 and Pancreatic Neoplasms
 Leukemia Antibodies  >1 publications with MRI1 and Leukemia
 Infertility, Male Antibodies  >1 publications with MRI1 and Infertility, Male
 Carcinoma Antibodies  >1 publications with MRI1 and Carcinoma
 Necrosis Antibodies  >1 publications with MRI1 and Necrosis

Organs/Tissues associated with anti-MRI1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with MRI1 and Brain
 Blood Antibodies  >4 publications with MRI1 and Blood
 Bone Antibodies  >2 publications with MRI1 and Bone
 Eye Antibodies  >1 publications with MRI1 and Eye
 Connective Tissue Antibodies  >1 publications with MRI1 and Connective Tissue
 Skin Antibodies  >1 publications with MRI1 and Skin
 Testis Antibodies  >1 publications with MRI1 and Testis
 Intestine Antibodies  >1 publications with MRI1 and Intestine
 Lung Antibodies  >1 publications with MRI1 and Lung
 Placenta Antibodies  >1 publications with MRI1 and Placenta
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