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Cathepsin V (CTSV) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS832143

MBS832143 is an antibody targeting CTSV. Also known as Cathepsin V antibody. Host: Mouse. Mouse monoclonal Cathepsin V antibody More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cathepsin V (CTSV), Monoclonal Antibody
Full Product Name
Cathepsin V antibody
Product Gene Name
Product Synonym Names
Monoclonal Cathepsin V; anti-Cathepsin V; CATL2; CTSL2; CATL 2; MGC125957; CTSU; CTSV
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BV55-1
Host
Mouse
Form/Format
Supplied in PBS buffer containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Purity/Purification
Cathepsin V antibody was purified by affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
37,329 Da
OMIM
603308
3D Structure
ModBase 3D Structure for O60911
Cross-Reactivity
Human
Immunogen
Cathepsin V antibody was raised in Mouse using synthetic peptide surrounding amino acid 21 of human cathepsin V as the immunogen.

Product Categories/Family for anti-CTSV antibody

Applications Tested/Suitable for anti-CTSV antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-CTSV antibody
IHC: 20-30 ug/ml
WB: 1-4 ug/ml

Other Notes

Small volumes of anti-CTSV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CTSV. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cathepsin V
NCBI Official Synonym Full Names
cathepsin V
NCBI Official Symbol
CTSV
NCBI Official Synonym Symbols
CTSU; CATL2; CTSL2
UniProt Protein Name
Cathepsin L2
UniProt Synonym Protein Names
Cathepsin U; Cathepsin V
Protein Family
UniProt Gene Name
CTSV
UniProt Synonym Gene Names
CATL2; CTSL2; CTSU
UniProt Entry Name
CATL2_HUMAN
NCBI Protein Information
cathepsin L2

NCBI Summary for CTSV

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]
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UniProt Comments for CTSV

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.

Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.22.15

Chromosomal Location of Human Ortholog: 9q22.2

Cellular Component: lysosomal lumen; extracellular space; neuron projection; microvillus; apical part of cell; extracellular region; nucleolus; perikaryon; secretory granule; external side of plasma membrane

Molecular Function: protein binding; histone binding; cysteine-type endopeptidase activity; protein complex binding; cysteine-type carboxypeptidase activity; aminopeptidase activity; kininogen binding; peptide binding; cysteine-type peptidase activity

Biological Process: extracellular matrix organization and biogenesis; hair follicle morphogenesis; response to glucocorticoid stimulus; Sertoli cell differentiation; antigen processing and presentation of exogenous peptide antigen via MHC class II; multicellular organismal aging; decidualization; proteolysis; cellular response to starvation; protein autoprocessing; extracellular matrix disassembly; response to glucose stimulus; autophagic cell death; spermatogenesis; nerve development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CTSV antibody

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