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SH2D2A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS832407

MBS832407 is an antibody targeting SH2D2A. Also known as SH2D2A antibody. Host: Mouse. Mouse monoclonal SH2D2A antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SH2D2A, Monoclonal Antibody
Full Product Name
SH2D2A antibody
Product Gene Name
Product Synonym Names
Monoclonal SH2D2A; Anti-SH2D2A; F2771; SCAP; TSAD; VRAP; SH2D2A; SHDA 2; SHDA-2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F3
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
SH2D2A antibody was purified by affinity chromatography.
Concentration
0.5-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
40,954 Da
OMIM
604514
3D Structure
ModBase 3D Structure for Q9NP31
Cross-Reactivity
Human
Immunogen
SH2D2A antibody was raised in Mouse using full length human recombinant protein of human SH2D2A produced in HEK293T cell as the immunogen.

Product Categories/Family for anti-SH2D2A antibody

Applications Tested/Suitable for anti-SH2D2A antibody
Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-SH2D2A antibody
IF: 1:100
FC: 1:100
IHC: 1:150
WB: 1:2000

Flow Cytometry (FC/FACS) of anti-SH2D2A antibody

Flow Cytometric analysis of HEK293T cells transfected with either recombinant SH2D2A protein (red) or empty vector (blue) stained using SH2D2A antibody
Mouse Anti-SH2D2A Monoclonal Antibody – Cat# MBS832407

Western Blot (WB) of anti-SH2D2A antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant SH2D2A protein (Right) or empty vector (Left) detected with SH2D2A antibody
Mouse Anti-SH2D2A Monoclonal Antibody, Western Blot (WB) – Cat# MBS832407

Immunohistochemistry (IHC) of anti-SH2D2A antibody

Immunohistochemical analysis of SH2D2A protein in paraffin embedded Carcinoma of Human liver tissue using SH2D2A antibody
Mouse Anti-SH2D2A Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS832407

Immunofluorescence (IF) of anti-SH2D2A antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant SH2D2A protein using SH2D2A antibody
Mouse Anti-SH2D2A Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS832407

Other Notes

Small volumes of anti-SH2D2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SH2D2A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SH2 domain-containing protein 2A isoform 2
NCBI Official Synonym Full Names
SH2 domain containing 2A
NCBI Official Symbol
SH2D2A
NCBI Official Synonym Symbols
SCAP; TSAD; VRAP; F2771
UniProt Protein Name
SH2 domain-containing protein 2A
UniProt Synonym Protein Names
SH2 domain-containing adapter protein; T cell-specific adapter protein; TSAd; VEGF receptor-associated protein
UniProt Gene Name
SH2D2A
UniProt Synonym Gene Names
SCAP; TSAD; VRAP; TSAd
UniProt Entry Name
SH22A_HUMAN
NCBI Protein Information
SH2 domain-containing protein 2A

NCBI Summary for SH2D2A

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
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UniProt Comments for SH2D2A

TSAd: an adaptor protein that may facilitate and regulate interaction of KDR with effector proteins important to endothelial cell survival and proliferation. May play a role in the CD4-p56- LCK-dependent signal transduction pathway in T cells. Could also play an important role in normal and pathological angiogenesis.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol

Molecular Function: protein binding; SH3/SH2 adaptor activity; SH3 domain binding

Biological Process: cell proliferation; positive regulation of signal transduction; angiogenesis; vascular endothelial growth factor receptor signaling pathway; signal transduction; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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