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PYCR2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS833160

MBS833160 is an antibody targeting PYCR2. Also known as PYCR2 antibody. Host: Mouse. Mouse monoclonal PYCR2 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PYCR2, Monoclonal Antibody
Full Product Name
PYCR2 antibody
Product Gene Name
Product Synonym Names
Monoclonal PYCR2; Anti-PYCR2; Pyrroline-5-Carboxylate Reductase Family Member 2; P5CR2; PYCR2; PYCR 2; PYCR-2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2A5
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
PYCR2 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
33,637 Da
3D Structure
ModBase 3D Structure for Q96C36
Cross-Reactivity
Human, Monkey
Immunogen
PYCR2 antibody was raised in mouse using a full length recombinant protein of human PYCR2 (NP_037460) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-PYCR2 antibody

Applications Tested/Suitable for anti-PYCR2 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-PYCR2 antibody
FC: 1:100
IF: 1:100
WB: 1:500-2000

Flow Cytometry (FC/FACS) of anti-PYCR2 antibody

Flow Cytometric analysis of Hela cells using PYCR2 antibody (Red), compared to a nonspecific negative control antibody (Blue).
Mouse Anti-PYCR2 Monoclonal Antibody – Cat# MBS833160

Western Blot (WB) of anti-PYCR2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PYCR2 protein (Right) or empty vector (Left) detected with PYCR2 antibody
Mouse Anti-PYCR2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS833160

Immunofluorescence (IF) of anti-PYCR2 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant PYCR2 protein using PYCR2 antibody
Mouse Anti-PYCR2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS833160

Other Notes

Small volumes of anti-PYCR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PYCR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pyrroline-5-carboxylate reductase 2 isoform 1
NCBI Official Synonym Full Names
pyrroline-5-carboxylate reductase family, member 2
NCBI Official Symbol
PYCR2
NCBI Official Synonym Symbols
HLD10; P5CR2
UniProt Protein Name
Pyrroline-5-carboxylate reductase 2
UniProt Gene Name
PYCR2
UniProt Synonym Gene Names
P5C reductase 2; P5CR 2
UniProt Entry Name
P5CR2_HUMAN
NCBI Protein Information
pyrroline-5-carboxylate reductase 2

NCBI Summary for PYCR2

This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
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UniProt Comments for PYCR2

PYCR2: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Belongs to the pyrroline-5-carboxylate reductase family.

Protein type: Oxidoreductase; Amino Acid Metabolism - arginine and proline; EC 1.5.1.2

Chromosomal Location of Human Ortholog: 1q42.12

Cellular Component: cytoplasm

Molecular Function: pyrroline-5-carboxylate reductase activity

Disease: Leukodystrophy, Hypomyelinating, 10
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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