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IGF2BP2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS833352

MBS833352 is an antibody targeting IGF2BP2. Also known as IGF2BP2 antibody. Host: Mouse. Mouse monoclonal IGF2BP2 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IGF2BP2, Monoclonal Antibody
Full Product Name
IGF2BP2 antibody
Product Gene Name
anti-IGF2BP2 antibody
Product Synonym Names
Monoclonal IGF2BP2; Anti-IGF2BP2; Insulin-Like Growth Factor 2 mRNA Binding Protein 2; IMP-2; IMP2; VICKZ2; p62; IGF2BP2; IGF2BP 2; IGF2BP-2; IGF-2 BP2; IGF 2-BP 2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4C4
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
IGF2BP2 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
90,360 Da
OMIM
605303
3D Structure
ModBase 3D Structure for Q9Y6A5
Cross-Reactivity
Human, Dog, Monkey
Immunogen
IGF2BP2 antibody was raised in mouse using a full length recombinant protein of human IGF2BP2 (NP_006333) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-IGF2BP2 antibody

Cytokines & Growth Factors
Applications Tested/Suitable for anti-IGF2BP2 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes for anti-IGF2BP2 antibody
FC: 1:100, IF: 1:100, IHC: 1:50

Western Blot (WB) of anti-IGF2BP2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant IGF2BP2 protein (Right) or empty vector (Left) detected with IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody – Cat# MBS833352

Immunohistochemistry (IHC) of anti-IGF2BP2 antibody

Immunohistochemical analysis of IGF2BP2 protein in paraffin embedded Human Kidney tissue using IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS833352

Immunofluorescence (IF) of anti-IGF2BP2 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant IGF2BP2 protein using IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS833352

Other Notes

Small volumes of anti-IGF2BP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF2BP2. It may not necessarily be applicable to this product.

NCBI GI #
5454102
NCBI GeneID
10460
NCBI Accession #
NP_006333
UniProt Primary Accession #
Q9Y6A5
UniProt Secondary Accession #
Q2NKK4; Q3KQS5; Q9UMQ1
UniProt Related Accession #
Q9Y6A5
GenBank Nucleotide #
NM_006342.2
NCBI Official Full Name
transforming acidic coiled-coil-containing protein 3
NCBI Official Synonym Full Names
transforming, acidic coiled-coil containing protein 3
NCBI Official Symbol
TACC3
NCBI Official Synonym Symbols
ERIC1; ERIC-1
UniProt Protein Name
Transforming acidic coiled-coil-containing protein 3
UniProt Synonym Protein Names
ERIC-1
Protein Family
Insulin-like growth factor 2 mRNA-binding protein
UniProt Gene Name
TACC3
UniProt Synonym Gene Names
ERIC1
UniProt Entry Name
TACC3_HUMAN
NCBI Protein Information
transforming acidic coiled-coil-containing protein 3

NCBI Summary for IGF2BP2

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011]
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UniProt Comments for IGF2BP2

TACC3: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May be involved in the control of cell growth and differentiation. May contribute to cancer. Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2. Interacts with GCN5L2 and PCAF. Up-regulated in various cancer cell lines. Belongs to the TACC family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: centrosome; cytoplasm

Molecular Function: protein domain specific binding; protein binding

Biological Process: cell proliferation; regulation of microtubule-based process; cytoplasmic sequestering of transcription factor; astral microtubule organization and biogenesis; neurogenesis; regulation of cell cycle; response to hypoxia; hemopoiesis; cerebral cortex development; microtubule cytoskeleton organization and biogenesis; interkinetic nuclear migration

Disease: Bladder Cancer
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Research Articles on IGF2BP2

1. findings suggest that TACC3 could be recruited as a bridge to cooperatively mediate between the HIF-2alpha PAS-B.ARNT PAS-B complex, thereby participating more directly in HIF-dependent gene transcription than previously anticipated

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IGF2BP2 antibody

 Reference Product  PubMed Publications
 CKAP5 antibody  >12 publications with IGF2BP2 and CKAP5
 AURKA antibody  >11 publications with IGF2BP2 and AURKA
 AURKB antibody  >3 publications with IGF2BP2 and AURKB
 ILK antibody  >3 publications with IGF2BP2 and ILK
 NDEL1 antibody  >2 publications with IGF2BP2 and NDEL1
 FAM161B antibody  >1 publications with IGF2BP2 and FAM161B
 UBC antibody  >1 publications with IGF2BP2 and UBC
 CDK1 antibody  >1 publications with IGF2BP2 and CDK1

Pathways associated with anti-IGF2BP2 antibody

 Products by Pathway  Pathway Diagram
 Aurora A Signaling Pathway antibodies  Aurora A Signaling Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram

Diseases associated with anti-IGF2BP2 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >9 publications with IGF2BP2 and Adenocarcinoma
 Urinary Bladder Neoplasms Antibodies  >8 publications with IGF2BP2 and Urinary Bladder Neoplasms
 Lung Neoplasms Antibodies  >7 publications with IGF2BP2 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >6 publications with IGF2BP2 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >6 publications with IGF2BP2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >6 publications with IGF2BP2 and Nervous System Diseases
 Lung Diseases Antibodies  >6 publications with IGF2BP2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >4 publications with IGF2BP2 and Cardiovascular Diseases
 Liver Neoplasms Antibodies  >2 publications with IGF2BP2 and Liver Neoplasms
 Thyroid Diseases Antibodies  >2 publications with IGF2BP2 and Thyroid Diseases

Organs/Tissues associated with anti-IGF2BP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >13 publications with IGF2BP2 and Lung
 Brain Antibodies  >10 publications with IGF2BP2 and Brain
 Bladder Antibodies  >9 publications with IGF2BP2 and Bladder
 Testis Antibodies  >5 publications with IGF2BP2 and Testis
 Liver Antibodies  >5 publications with IGF2BP2 and Liver
 Blood Antibodies  >4 publications with IGF2BP2 and Blood
 Ovary Antibodies  >4 publications with IGF2BP2 and Ovary
 Bone Antibodies  >4 publications with IGF2BP2 and Bone
 Thymus Antibodies  >4 publications with IGF2BP2 and Thymus
 Embryonic Tissue Antibodies  >4 publications with IGF2BP2 and Embryonic Tissue
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