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IGF2BP2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS833538

MBS833538 is an antibody targeting IGF2BP2. Also known as IGF2BP2 antibody. Host: Mouse. Mouse monoclonal IGF2BP2 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IGF2BP2, Monoclonal Antibody
Full Product Name
IGF2BP2 antibody
Product Gene Name
Product Synonym Names
Monoclonal IGF2BP2; Anti-IGF2BP2; Insulin-Like Growth Factor 2 mRNA Binding Protein 2; IMP-2; IMP2; VICKZ2; p62; IGF2BP2; IGF2BP 2; IGF2BP-2; IGF-2 BP2; IGF 2-BP 2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5G3
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
IGF2BP2 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
58,578 Da
OMIM
608289
3D Structure
ModBase 3D Structure for Q9Y6M1
Cross-Reactivity
Human, Monkey
Immunogen
IGF2BP2 antibody was raised in mouse using a full length recombinant protein of human IGF2BP2 (NP_006539) produced in HEK293T cells, as the immunogen.
Applications Tested/Suitable for anti-IGF2BP2 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
Application Notes for anti-IGF2BP2 antibody
FC: 1:100, IF: 1:100, IHC: 1:50

Western Blot (WB) of anti-IGF2BP2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant IGF2BP2 protein (Right) or empty vector (Left) detected with IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody – Cat# MBS833538

Immunohistochemistry (IHC) of anti-IGF2BP2 antibody

Immunohistochemical analysis of IGF2BP2 protein in paraffin embedded Human Kidney tissue using IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS833538

Immunofluorescence (IF) of anti-IGF2BP2 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant IGF2BP2 protein using IGF2BP2 antibody
Mouse Anti-IGF2BP2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS833538

Other Notes

Small volumes of anti-IGF2BP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF2BP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor 2 mRNA-binding protein 2 isoform a
NCBI Official Synonym Full Names
insulin-like growth factor 2 mRNA binding protein 2
NCBI Official Symbol
IGF2BP2
NCBI Official Synonym Symbols
IMP2; IMP-2; VICKZ2
UniProt Protein Name
Insulin-like growth factor 2 mRNA-binding protein 2
UniProt Synonym Protein Names
Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2
UniProt Gene Name
IGF2BP2
UniProt Synonym Gene Names
IMP2; VICKZ2; IGF2 mRNA-binding protein 2; IMP-2
UniProt Entry Name
IF2B2_HUMAN
NCBI Protein Information
insulin-like growth factor 2 mRNA-binding protein 2

NCBI Summary for IGF2BP2

This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms. [provided by RefSeq, May 2014]
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UniProt Comments for IGF2BP2

IGF2BP2: Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs. Belongs to the RRM IMP/VICKZ family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 3q27.2

Cellular Component: cytoskeleton; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; mRNA 3'-UTR binding; nucleotide binding; translation regulator activity; mRNA 5'-UTR binding

Biological Process: anatomical structure morphogenesis; mRNA transport; negative regulation of translation; gene expression; regulation of cytokine biosynthetic process

Disease: Diabetes Mellitus, Noninsulin-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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