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TUBAL3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS833821

MBS833821 is an antibody targeting TUBAL3. Also known as TUBAL3 antibody. Host: Mouse. Mouse monoclonal TUBAL3 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TUBAL3, Monoclonal Antibody
Full Product Name
TUBAL3 antibody
Product Gene Name
Product Synonym Names
Monoclonal TUBAL3; Anti-TUBAL3; Tubulin alpha-like 3; FLJ21665; MGC119347; Tubulin alpha chain-like 3; TUBAL3; TUBAL 3; TUBAL-3
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
5F10
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
TUBAL3 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
20,180 Da
OMIM
609068
3D Structure
ModBase 3D Structure for Q8N907
Cross-Reactivity
Human
Immunogen
TUBAL3 antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 150-446 of human TUBAL3 (NP_689867) produced in E Coli as the immunogen.

Product Categories/Family for anti-TUBAL3 antibody

Applications Tested/Suitable for anti-TUBAL3 antibody
Western Blot (WB)
Application Notes for anti-TUBAL3 antibody
WB: 1:2000

Western Blot (WB) of anti-TUBAL3 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TUBAL3 protein (Right) or empty vector (Left) detected with TUBAL3 antibody
Mouse Anti-TUBAL3 Monoclonal Antibody – Cat# MBS833821

Other Notes

Small volumes of anti-TUBAL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBAL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DAN domain family member 5
NCBI Official Synonym Full Names
DAN domain family member 5, BMP antagonist
NCBI Official Symbol
DAND5
NCBI Official Synonym Symbols
SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3
UniProt Protein Name
DAN domain family member 5
UniProt Synonym Protein Names
Cerberus-like protein 2; Cerl-2; Cysteine knot superfamily 1, BMP antagonist 3; Gremlin-3
Protein Family
UniProt Gene Name
DAND5
UniProt Synonym Gene Names
CER2; CKTSF1B3; GREM3; SP1; Cerl-2
UniProt Entry Name
DAND5_HUMAN
NCBI Protein Information
DAN domain family member 5

NCBI Summary for TUBAL3

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
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UniProt Comments for TUBAL3

DAND5: Seems to play a role in the correct specification of the left-right axis. May antagonize NODAL and BMP4 signaling. Cystine knot-containing proteins play important roles during development, organogenesis, tissue growth and differentiation. Belongs to the DAN family.

Protein type: Cell development/differentiation; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular region

Molecular Function: morphogen activity

Biological Process: negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of BMP signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TUBAL3 antibody

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