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SRR Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS834099

MBS834099 is an antibody targeting SRR. Also known as SRR antibody. Host: Mouse. Mouse monoclonal SRR antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SRR, Monoclonal Antibody
Full Product Name
SRR antibody
Product Gene Name
anti-SRR antibody
Product Synonym Names
Monoclonal SRR; Anti-SRR; Serine Racemase; ILV1; ISO1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7G6
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
SRR antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
36,566 Da
OMIM
606477
3D Structure
ModBase 3D Structure for Q9GZT4
Cross-Reactivity
Human
Immunogen
SRR antibody was raised in mouse using a full length recombinant protein of human SRR (NP_068766) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-SRR antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-SRR antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-SRR antibody
IF: 1:100
FC: 1:100
WB: 1:500

Flow Cytometry (FC/FACS) of anti-SRR antibody

Flow Cytometric analysis of HEK293T cells transfected with either recombinant SRR protein (red) or empty vector (blue) stained using SRR antibody
Mouse Anti-SRR Monoclonal Antibody – Cat# MBS834099

Western Blot (WB) of anti-SRR antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant SRR protein (Right) or empty vector (Left) detected with SRR antibody
Mouse Anti-SRR Monoclonal Antibody, Western Blot (WB) – Cat# MBS834099

Immunofluorescence (IF) of anti-SRR antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant SRR protein using SRR antibody
Mouse Anti-SRR Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS834099

Other Notes

Small volumes of anti-SRR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SRR. It may not necessarily be applicable to this product.

NCBI GI #
11345492
NCBI GeneID
63826
NCBI Accession #
NP_068766
UniProt Primary Accession #
Q9GZT4
UniProt Secondary Accession #
Q6IA55; D3DTI5
UniProt Related Accession #
Q9GZT4
GenBank Nucleotide #
NM_021947.1
NCBI Official Full Name
serine racemase isoform a
NCBI Official Synonym Full Names
serine racemase
NCBI Official Symbol
SRR
NCBI Official Synonym Symbols
ILV1; ISO1
UniProt Protein Name
Serine racemase
UniProt Synonym Protein Names
D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase
Protein Family
Probable serine racemase
UniProt Gene Name
SRR
UniProt Entry Name
SRR_HUMAN
NCBI Protein Information
serine racemase

UniProt Comments for SRR

SRR: Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. Belongs to the serine/threonine dehydratase family.

Protein type: Isomerase; EC 4.3.1.17; EC 4.3.1.18; EC 5.1.1.18; Amino Acid Metabolism - glycine, serine and threonine

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: cell soma; apical part of cell; cytoplasm; plasma membrane

Molecular Function: protein homodimerization activity; glycine binding; threonine racemase activity; L-serine ammonia-lyase activity; magnesium ion binding; calcium ion binding; D-serine ammonia-lyase activity; serine racemase activity; ATP binding; pyridoxal phosphate binding; PDZ domain binding

Biological Process: response to drug; pyruvate biosynthetic process; L-serine metabolic process; response to morphine; response to lipopolysaccharide; brain development; serine family amino acid metabolic process; aging; protein homotetramerization
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Research Articles on SRR

1. In serine racemase, similarly to the related enzyme alanine racemase, the unprotonated pyridoxal-5'-phosphate -substrate intermediate is stabilized mostly due to solvation effects contributed by water molecules and active-site residues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SRR antibody

 Reference Product  PubMed Publications
 SHMT1 antibody  >3 publications with SRR and SHMT1
 UBC antibody  >1 publications with SRR and UBC
 SDS antibody  >1 publications with SRR and SDS

Pathways associated with anti-SRR antibody

 Products by Pathway  Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Serine And Glycine Biosynthesis Pathway antibodies  Serine And Glycine Biosynthesis Pathway Diagram

Diseases associated with anti-SRR antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >40 publications with SRR and Cardiovascular Diseases
 Liver Diseases Antibodies  >16 publications with SRR and Liver Diseases
 Hypertension Antibodies  >16 publications with SRR and Hypertension
 Genital Diseases, Male Antibodies  >15 publications with SRR and Genital Diseases, Male
 Liver Neoplasms Antibodies  >14 publications with SRR and Liver Neoplasms
 Hepatitis Antibodies  >14 publications with SRR and Hepatitis
 Disease Models, Animal Antibodies  >13 publications with SRR and Disease Models, Animal
 Infertility, Male Antibodies  >9 publications with SRR and Infertility, Male
 Kidney Diseases Antibodies  >9 publications with SRR and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >5 publications with SRR and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-SRR antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >86 publications with SRR and Blood
 Brain Antibodies  >53 publications with SRR and Brain
 Liver Antibodies  >44 publications with SRR and Liver
 Heart Antibodies  >40 publications with SRR and Heart
 Lung Antibodies  >39 publications with SRR and Lung
 Kidney Antibodies  >35 publications with SRR and Kidney
 Bone Antibodies  >31 publications with SRR and Bone
 Muscle Antibodies  >14 publications with SRR and Muscle
 Vascular Antibodies  >13 publications with SRR and Vascular
 Stomach Antibodies  >13 publications with SRR and Stomach
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