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MRAS Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS834809

MBS834809 is an antibody targeting MRAS. Also known as MRAS antibody. Host: Mouse. Mouse monoclonal MRAS antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MRAS, Monoclonal Antibody
Full Product Name
MRAS antibody
Product Gene Name
Product Synonym Names
Monoclonal MRAS; Anti-MRAS; Muscle RAS oncogene homolog; RRAS3; Ras related protein R-Ras3; FLJ42964; Muscle and Microspikes RAS
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3C4
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
MRAS antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
15,542 Da
OMIM
608435
3D Structure
ModBase 3D Structure for O14807
Cross-Reactivity
Human
Immunogen
MRAS antibody was raised in mouse using a full length recombinant protein of human MRAS (NP_036351) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-MRAS antibody

Applications Tested/Suitable for anti-MRAS antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-MRAS antibody
FC: 1:100
IF: 1:100
WB: 1:2000

Flow Cytometry (FC/FACS) of anti-MRAS antibody

Flow Cytometric analysis of Jurkat cells using MRAS antibody (Red), compared to a nonspecific negative control antibody (Blue).
Mouse Anti-MRAS Monoclonal Antibody – Cat# MBS834809

Western Blot (WB) of anti-MRAS antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MRAS protein (Right) or empty vector (Left) detected with MRAS antibody
Mouse Anti-MRAS Monoclonal Antibody, Western Blot (WB) – Cat# MBS834809

Immunofluorescence (IF) of anti-MRAS antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant MRAS protein using MRAS antibody
Mouse Anti-MRAS Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS834809

Other Notes

Small volumes of anti-MRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRAS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras-related protein M-Ras isoform 1
NCBI Official Synonym Full Names
muscle RAS oncogene homolog
NCBI Official Symbol
MRAS
NCBI Official Synonym Symbols
M-RAs; RRAS3; R-RAS3
UniProt Protein Name
Ras-related protein M-Ras
UniProt Synonym Protein Names
Ras-related protein R-Ras3
Protein Family
UniProt Gene Name
MRAS
UniProt Synonym Gene Names
RRAS3
UniProt Entry Name
RASM_HUMAN
NCBI Protein Information
ras-related protein M-Ras

NCBI Summary for MRAS

This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for MRAS

MRas: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Belongs to the small GTPase superfamily. Ras family.

Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric; Oncoprotein

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: plasma membrane

Molecular Function: GTPase activity; GTP binding; GTP-dependent protein binding

Biological Process: muscle development; metabolic process; multicellular organismal development; Ras protein signal transduction; actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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