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SMS Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS834810

MBS834810 is an antibody targeting SMS. Also known as SMS antibody. Host: Mouse. Mouse monoclonal SMS antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMS, Monoclonal Antibody
Full Product Name
SMS antibody
Product Gene Name
Product Synonym Names
Monoclonal SMS; Anti-SMS; Spermine synthase; SPMSY; MRSR; SpS; Snyder-Robinson X-linked mental retardation syndrome; Spermidine aminopropyltransferase
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3A8
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
SMS antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
35,278 Da
OMIM
300105
3D Structure
ModBase 3D Structure for P52788
Cross-Reactivity
Human
Immunogen
SMS antibody was raised in mouse using a full length recombinant protein of human SMS (NP_004586) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-SMS antibody

Applications Tested/Suitable for anti-SMS antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-SMS antibody
FC: 1:100
IF: 1:100
IHC: 1:150
WB: 1:2000

Western Blot (WB) of anti-SMS antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant SMS protein (Right) or empty vector (Left) detected with SMS antibody
Mouse Anti-SMS Monoclonal Antibody – Cat# MBS834810

Immunohistochemistry (IHC) of anti-SMS antibody

Immunohistochemical analysis of SMS protein in paraffin embedded Human prostate tissue using SMS antibody
Mouse Anti-SMS Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS834810

Immunofluorescence (IF) of anti-SMS antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant SMS protein using SMS antibody
Mouse Anti-SMS Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS834810

Other Notes

Small volumes of anti-SMS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SMS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
spermine synthase isoform 1
NCBI Official Synonym Full Names
spermine synthase
NCBI Official Symbol
SMS
NCBI Official Synonym Symbols
SRS; SpS; MRSR; SPMSY
UniProt Protein Name
Spermine synthase
UniProt Synonym Protein Names
Spermidine aminopropyltransferase
Protein Family
UniProt Gene Name
SMS
UniProt Synonym Gene Names
SPMSY
UniProt Entry Name
SPSY_HUMAN
NCBI Protein Information
spermine synthase

NCBI Summary for SMS

This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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UniProt Comments for SMS

SMS: an ubiquitous enzyme of polyamine metabolism. Synthesizes spermine from spermidine.

Protein type: Other Amino Acids Metabolism - glutathione; Transferase; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - arginine and proline; EC 2.5.1.22; Amino Acid Metabolism - cysteine and methionine

Chromosomal Location of Human Ortholog: Xp22.1

Cellular Component: cytosol

Molecular Function: spermidine synthase activity; spermine synthase activity

Biological Process: methionine metabolic process; spermine biosynthetic process; polyamine metabolic process

Disease: Mental Retardation, X-linked, Syndromic, Snyder-robinson Type
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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