Peroxiredoxin III (PRDX3) Antibody – Mouse Monoclonal

PRDX3: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Belongs to the AhpC/TSA family.

Protein type: EC 1.11.1.15; Oxidoreductase

Cellular Component: mitochondrion; cytoplasm; early endosome; IkappaB kinase complex; cytosol; myelin sheath

Molecular Function: antioxidant activity; protein C-terminus binding; identical protein binding; peroxidase activity; thioredoxin peroxidase activity; peroxiredoxin activity; caspase inhibitor activity; oxidoreductase activity; kinase binding; protein kinase binding

Biological Process: negative regulation of kinase activity; mitochondrion organization and biogenesis; response to lipopolysaccharide; negative regulation of caspase activity; activation of NF-kappaB transcription factor; peptidyl-cysteine oxidation; response to hydrogen peroxide; regulation of mitochondrial membrane potential; hydrogen peroxide catabolic process; positive regulation of cell proliferation; myeloid cell differentiation; negative regulation of neuron apoptosis; response to oxidative stress; negative regulation of apoptosis; maternal placenta development