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IkB EPSILON Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835044

MBS835044 is an antibody targeting IkB Epsilon. Also known as IkB Epsilon antibody. Host: Rabbit. Rabbit polyclonal IkB Epsilon antibody More details

$710 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IkB Epsilon, Polyclonal Antibody
Full Product Name
IkB Epsilon antibody
Product Gene Name
anti-IkB Epsilon antibody
Product Synonym Names
Polyclonal IkB Epsilon; Anti-IkB Epsilon; NF-kappa-B inhibitor epsilon; IkappaBepsilon; I-kappa-B-epsilon; NFKBIE; IkB-E; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; NF-kappa-BIE; Ab 22; IKBE; IkB-epsilon
Clonality
Polyclonal
Host
Rabbit
Form/Format
Supplied in liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
IkB Epsilon antibody was purified by immunoaffinity chromatography.
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
39,200 Da
3D Structure
ModBase 3D Structure for O54910
Cross-Reactivity
Human, Mouse
Immunogen
IkB Epsilon antibody was raised in Rabbit using the peptide sequence around aa 20~24 (I-E-S-L-R) derived from Human IkB-E as the immunogen.

Product Categories/Family for anti-IkB Epsilon antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-IkB Epsilon antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-IkB Epsilon antibody
IHC: 1:50-1:100
WB: 1:500-1:1000

Immunohistochemistry (IHC) of anti-IkB Epsilon antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-e antibody (left) or the same antibody preincubated with with blocking peptide (right)
Rabbit Anti-IkB EPSILON Polyclonal Antibody – Cat# MBS835044

Western Blot (WB) of anti-IkB Epsilon antibody

Western Blot analysis of extracts from Hela, 293 and HepG2 cells using IkB-E antibody
Rabbit Anti-IkB EPSILON Polyclonal Antibody, Western Blot (WB) – Cat# MBS835044

Other Notes

Small volumes of anti-IkB Epsilon antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IkB Epsilon. It may not necessarily be applicable to this product.

NCBI GI #
2739158
NCBI GeneID
18037
NCBI Accession #
AAB97517.1
UniProt Primary Accession #
O54910
UniProt Secondary Accession #
Q3U686; Q9CZZ9; Q9D7U3
UniProt Related Accession #
O54910
NCBI Official Full Name
IkB epsilon
NCBI Official Synonym Full Names
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
NCBI Official Symbol
Nfkbie
NCBI Official Synonym Symbols
IKBE; IkB-E; ikB-epsilon; NF-kappa-BIE; I-kappa-B-epsilon
UniProt Protein Name
NF-kappa-B inhibitor epsilon
UniProt Synonym Protein Names
I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilon
Protein Family
NF-kappa-B inhibitor
UniProt Gene Name
Nfkbie
UniProt Synonym Gene Names
Ikbe; NF-kappa-BIE; IkB-E; IkB-epsilon; IkappaBepsilon
UniProt Entry Name
IKBE_MOUSE
NCBI Protein Information
NF-kappa-B inhibitor epsilon

UniProt Comments for IkB Epsilon

IkB-epsilon: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit. Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages. Belongs to the NF-kappa-B inhibitor family.

Protein type: Inhibitor; DNA-binding

Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; cytoplasm

Molecular Function: protein binding

Biological Process: negative regulation of transcription, DNA-dependent; D-serine transport
Show more

Research Articles on IkB Epsilon

1. The data imply that regulation of these c-Rel-dependent lymphoid responses is a non-redundant function of IkappaBepsilon.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IkB Epsilon antibody

 Reference Product  PubMed Publications
 Rel antibody  >16 publications with IkB Epsilon and Rel
 Rela antibody  >12 publications with IkB Epsilon and Rela
 Ikbkb antibody  >8 publications with IkB Epsilon and Ikbkb
 Relb antibody  >6 publications with IkB Epsilon and Relb
 Nfkb1 antibody  >5 publications with IkB Epsilon and Nfkb1
 Nfkb2 antibody  >3 publications with IkB Epsilon and Nfkb2
 Chuk antibody  >3 publications with IkB Epsilon and Chuk
 Tnfaip3 antibody  >1 publications with IkB Epsilon and Tnfaip3

Pathways associated with anti-IkB Epsilon antibody

 Products by Pathway  Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Signaling Pathway antibodies  Apoptosis Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram

Diseases associated with anti-IkB Epsilon antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >15 publications with IkB Epsilon and Necrosis
 Inflammation Antibodies  >11 publications with IkB Epsilon and Inflammation
 Arthritis, Rheumatoid Antibodies  >5 publications with IkB Epsilon and Arthritis, Rheumatoid
 Lung Diseases Antibodies  >3 publications with IkB Epsilon and Lung Diseases
 Kidney Diseases Antibodies  >2 publications with IkB Epsilon and Kidney Diseases
 Neoplasms, Experimental Antibodies  >1 publications with IkB Epsilon and Neoplasms, Experimental
 Atherosclerosis Antibodies  >1 publications with IkB Epsilon and Atherosclerosis
 Cell Transformation, Neoplastic Antibodies  >1 publications with IkB Epsilon and Cell Transformation, Neoplastic
 Edema Antibodies  >1 publications with IkB Epsilon and Edema
 Pneumonia Antibodies  >1 publications with IkB Epsilon and Pneumonia

Organs/Tissues associated with anti-IkB Epsilon antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with IkB Epsilon and Blood
 Spleen Antibodies  >4 publications with IkB Epsilon and Spleen
 Intestine Antibodies  >3 publications with IkB Epsilon and Intestine
 Bone Marrow Antibodies  >3 publications with IkB Epsilon and Bone Marrow
 Joint Antibodies  >2 publications with IkB Epsilon and Joint
 Skin Antibodies  >1 publications with IkB Epsilon and Skin
 Lymph Node Antibodies  >1 publications with IkB Epsilon and Lymph Node
 Brain Antibodies  >1 publications with IkB Epsilon and Brain
 Thymus Antibodies  >1 publications with IkB Epsilon and Thymus
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