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Tetraspan 1 (TSPAN1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835058

MBS835058 is an antibody targeting TSPAN1. Also known as Tetraspan 1 antibody. Host: Rabbit. Affinity purified Rabbit polyclonal Tetraspan 1 antibody More details

$1565 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tetraspan 1 (TSPAN1), Polyclonal Antibody
Full Product Name
Tetraspan 1 antibody
Product Gene Name
anti-TSPAN1 antibody
Product Synonym Names
Polyclonal Tetraspan 1; Anti-Tetraspan 1; tetraspanin-1; Tetraspan 1; TSPAN1; tetraspanin 1; TM4C; tetraspan 1; TM4SF; Tetraspan -1; NET1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
Tetraspan 1 antibody was purified by antigen-affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
26 kDa
OMIM
613170
Cross-Reactivity
Human

Product Categories/Family for anti-TSPAN1 antibody

Cell Biology; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-TSPAN1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-TSPAN1 antibody
IHC-P: 1:100-1:500
WB: 1:500-1:3000

Immunohistochemistry (IHC) of anti-TSPAN1 antibody

Immunohistochemical staining of paraffin-embedded Colon ca using Tetraspan 1 antibody at a dilution of 1:500
Rabbit Anti-TSPAN1 Polyclonal Antibody – Cat# MBS835058

Western Blot (WB) of anti-TSPAN1 antibody

Western blot analysis of 30 ug whole cell lysate (A: H1299) using a 12 % SDS PAGE gel and Tetraspan 1 antibody at a dilution of 1:500
Rabbit Anti-TSPAN1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS835058

Other Notes

Small volumes of anti-TSPAN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSPAN1. It may not necessarily be applicable to this product.

NCBI GI #
21264578
NCBI GeneID
10103
NCBI Accession #
NP_005718.2
UniProt Secondary Accession #
O60745; Q5VST0; D3DQ14
UniProt Related Accession #
O60635
GenBank Nucleotide #
NM_005727.3
NCBI Official Full Name
tetraspanin-1
NCBI Official Synonym Full Names
tetraspanin 1
NCBI Official Symbol
TSPAN1
NCBI Official Synonym Symbols
NET1; TM4C; TM4SF
UniProt Protein Name
Tetraspanin-1
UniProt Synonym Protein Names
Tetraspan NET-1; Tetraspanin TM4-C
UniProt Gene Name
TSPAN1
UniProt Synonym Gene Names
Tspan-1
UniProt Entry Name
TSN1_HUMAN
NCBI Protein Information
tetraspanin-1

NCBI Summary for TSPAN1

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
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UniProt Comments for TSPAN1

TSPAN1: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: membrane; perinuclear region of cytoplasm; lysosomal membrane; cytoplasm; integral to membrane; plasma membrane; vesicle

Molecular Function: protein binding; thiamin uptake transmembrane transporter activity

Biological Process: cell proliferation; cell migration; protein stabilization; positive regulation of endocytosis
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Research Articles on TSPAN1

1. TSPAN1 was proved to induce migration, and so up-regulation of TSPAN1 by miR-200a may explain why over-expressing miR-200a promotes NSCLC cells migration

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TSPAN1 antibody

 Reference Product  PubMed Publications
 CD9 antibody  >4 publications with TSPAN1 and CD9
 MDK antibody  >2 publications with TSPAN1 and MDK
 CD151 antibody  >1 publications with TSPAN1 and CD151
 SLC19A2 antibody  >1 publications with TSPAN1 and SLC19A2

Diseases associated with anti-TSPAN1 antibody

 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >6 publications with TSPAN1 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with TSPAN1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with TSPAN1 and Liver Neoplasms
 Ovarian Diseases Antibodies  >2 publications with TSPAN1 and Ovarian Diseases
 Urinary Bladder Neoplasms Antibodies  >1 publications with TSPAN1 and Urinary Bladder Neoplasms
 Infertility, Female Antibodies  >1 publications with TSPAN1 and Infertility, Female
 Uterine Cervical Neoplasms Antibodies  >1 publications with TSPAN1 and Uterine Cervical Neoplasms
 Lung Diseases Antibodies  >1 publications with TSPAN1 and Lung Diseases
 Hyperplasia Antibodies  >1 publications with TSPAN1 and Hyperplasia
 Prostatic Diseases Antibodies  >1 publications with TSPAN1 and Prostatic Diseases

Organs/Tissues associated with anti-TSPAN1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with TSPAN1 and Liver
 Stomach Antibodies  >3 publications with TSPAN1 and Stomach
 Blood Antibodies  >2 publications with TSPAN1 and Blood
 Nerve Antibodies  >2 publications with TSPAN1 and Nerve
 Intestine Antibodies  >2 publications with TSPAN1 and Intestine
 Skin Antibodies  >1 publications with TSPAN1 and Skin
 Cervix Antibodies  >1 publications with TSPAN1 and Cervix
 Muscle Antibodies  >1 publications with TSPAN1 and Muscle
 Bladder Antibodies  >1 publications with TSPAN1 and Bladder
 Pancreas Antibodies  >1 publications with TSPAN1 and Pancreas
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