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SEC13L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835471

MBS835471 is an antibody targeting SEC13L1. Also known as SEC13L1 antibody. Host: Rabbit. Affinity purified Rabbit polyclonal SEC13L1 antibody More details

$1575 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SEC13L1, Polyclonal Antibody
Full Product Name
SEC13L1 antibody
Product Gene Name
anti-SEC13L1 antibody
Product Synonym Names
Polyclonal SEC13L1; Anti-SEC13L1; SEC13-related protein; SECL1 13; SEC13L1; SEC13 homolog (S. cerevisiae); SEC13R; SEC13; SECL1-13; npp-20; D3S1231E; SEC13-like 1 isoform; SEC13-like protein 1; protein SEC13 homolog
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
SEC13L1 antibody was purified by antigen-affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
36 kDa
OMIM
600152
3D Structure
ModBase 3D Structure for P55735
Cross-Reactivity
Human
Immunogen
SEC13L1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 319 of SEC13L1

Product Categories/Family for anti-SEC13L1 antibody

Cell Biology; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-SEC13L1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-SEC13L1 antibody
IHC-P: 1:100-1:500
WB: 1:500-1:3000

Immunohistochemistry (IHC) of anti-SEC13L1 antibody

Immunohistochemical staining of paraffin-embedded A549 xenograft using SEC13L1 antibody at a dilution of 1:100
Rabbit Anti-SEC13L1 Polyclonal Antibody – Cat# MBS835471

Western Blot (WB) of anti-SEC13L1 antibody

Western blot analysis of 30 ug of whole cell lysate (A: 293T; B: A431; C: H1299) using a 10 % SDS PAGE gel and SEC13L1 antibody at a dilution of 1:1000
Rabbit Anti-SEC13L1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS835471

Other Notes

Small volumes of anti-SEC13L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SEC13L1. It may not necessarily be applicable to this product.

NCBI GI #
119584482
NCBI GeneID
6396
NCBI Accession #
EAW64078.1
UniProt Primary Accession #
P55735
UniProt Secondary Accession #
Q5BJF0; Q9BRM6; Q9BUG7; A8MV37; B4DXJ1
UniProt Related Accession #
P55735
NCBI Official Full Name
SEC13-like 1 (S. cerevisiae), isoform CRA_b
NCBI Official Synonym Full Names
SEC13 homolog (S. cerevisiae)
NCBI Official Symbol
SEC13
NCBI Official Synonym Symbols
SEC13R; npp-20; SEC13L1; D3S1231E
UniProt Protein Name
Protein SEC13 homolog
UniProt Synonym Protein Names
SEC13-like protein 1; SEC13-related protein
UniProt Gene Name
SEC13
UniProt Synonym Gene Names
D3S1231E; SEC13L1; SEC13R
UniProt Entry Name
SEC13_HUMAN
NCBI Protein Information
protein SEC13 homolog

NCBI Summary for SEC13L1

The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008]
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UniProt Comments for SEC13L1

SEC13: Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Belongs to the WD repeat SEC13 family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p25-p24

Cellular Component: kinetochore; Golgi membrane; endoplasmic reticulum membrane; nuclear envelope; cytosol

Molecular Function: protein binding

Biological Process: COPII coating of Golgi vesicle; intracellular protein transport; ER to Golgi vesicle-mediated transport; antigen processing and presentation of peptide antigen via MHC class I; mRNA transport; cellular protein metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class II; protein amino acid N-linked glycosylation via asparagine; mitotic cell cycle; post-translational protein modification
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Research Articles on SEC13L1

1. When embedded in a three-dimensional matrix, Sec13-depleted Caco-2 cells form cysts but, unlike controls, are defective in lumen expansion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SEC13L1 antibody

 Reference Product  PubMed Publications
 SEC31A antibody  >21 publications with SEC13L1 and SEC31A
 SEC23A antibody  >16 publications with SEC13L1 and SEC23A
 NUP107 antibody  >7 publications with SEC13L1 and NUP107
 SEC31B antibody  >4 publications with SEC13L1 and SEC31B
 NUP160 antibody  >4 publications with SEC13L1 and NUP160
 NUP85 antibody  >4 publications with SEC13L1 and NUP85
 NUP98 antibody  >3 publications with SEC13L1 and NUP98
 NUP133 antibody  >2 publications with SEC13L1 and NUP133
 SEC24B antibody  >1 publications with SEC13L1 and SEC24B
 NUP37 antibody  >1 publications with SEC13L1 and NUP37

Pathways associated with anti-SEC13L1 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 ER To Golgi Transport Pathway antibodies  ER To Golgi Transport Pathway Diagram

Diseases associated with anti-SEC13L1 antibody

 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >2 publications with SEC13L1 and Vascular Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with SEC13L1 and Carcinoma, Hepatocellular
 Cardiovascular Diseases Antibodies  >2 publications with SEC13L1 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >2 publications with SEC13L1 and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with SEC13L1 and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with SEC13L1 and Liver Neoplasms
 Hypertrophy Antibodies  >2 publications with SEC13L1 and Hypertrophy
 Fatty Liver Antibodies  >2 publications with SEC13L1 and Fatty Liver
 Fibrosis Antibodies  >1 publications with SEC13L1 and Fibrosis

Organs/Tissues associated with anti-SEC13L1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with SEC13L1 and Liver
 Intestine Antibodies  >4 publications with SEC13L1 and Intestine
 Brain Antibodies  >4 publications with SEC13L1 and Brain
 Testis Antibodies  >3 publications with SEC13L1 and Testis
 Pancreas Antibodies  >3 publications with SEC13L1 and Pancreas
 Kidney Antibodies  >3 publications with SEC13L1 and Kidney
 Blood Antibodies  >3 publications with SEC13L1 and Blood
 Eye Antibodies  >2 publications with SEC13L1 and Eye
 Bone Antibodies  >2 publications with SEC13L1 and Bone
 Thymus Antibodies  >2 publications with SEC13L1 and Thymus
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