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SNTB2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS835687

MBS835687 is an antibody targeting SNTB2. Also known as SNTB2 antibody. Host: Rabbit. Affinity purified Rabbit polyclonal SNTB2 antibody More details

$1575 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SNTB2, Polyclonal Antibody
Full Product Name
SNTB2 antibody
Product Gene Name
anti-SNTB2 antibody
Product Synonym Names
Polyclonal SNTB2; Anti-SNTB2; SNT2B2; 59 kDa dystrophin-associated protein A1 basic component 2; SNTB-2; SNTB2; SNTB 2; syntrophin-3; SNT3; SNTL; beta-2-syntrophin; D16S2531E; EST25263; dystrophin-associated protein A1 59kD basic component 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
SNTB2 antibody was purified by antigen-affinity chromatography
Concentration
0.84 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
58 kDa
3D Structure
ModBase 3D Structure for Q61235
Cross-Reactivity
Human

Product Categories/Family for anti-SNTB2 antibody

Cell Biology; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-SNTB2 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-SNTB2 antibody
IF:1:100-1:500
ICC:1:100-1:500
IHC-P: 1:100-1:500
WB: 1:500-1:3000

Immunofluorescence (IF) of anti-SNTB2 antibody

Immunofluorescence analysis of methanol-fixed HeLa, using SNTB2 antibody at 1:200 dilution.
Rabbit Anti-SNTB2 Polyclonal Antibody – Cat# MBS835687

Western Blot (WB) of anti-SNTB2 antibody

Western blot analysis of 30 ug of whole cell lysate (A: Hep G2) using a 7.5 % SDS PAGE gel and SNTB2 antibody at a dilution of 1:3000
Rabbit Anti-SNTB2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS835687

Immunohistochemistry (IHC) of anti-SNTB2 antibody

Immunohistochemical staining of paraffin-embedded OVCAR3 xenograft using SNTB2 antibody at a dilution of 1:500
Rabbit Anti-SNTB2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS835687

Other Notes

Small volumes of anti-SNTB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SNTB2. It may not necessarily be applicable to this product.

NCBI GI #
219519541
NCBI GeneID
20650
NCBI Accession #
AAI45443.1
UniProt Primary Accession #
Q61235
UniProt Related Accession #
Q61235
NCBI Official Full Name
Sntb2 protein
NCBI Official Synonym Full Names
syntrophin, basic 2
NCBI Official Symbol
Sntb2
NCBI Official Synonym Symbols
Snt2
UniProt Protein Name
Beta-2-syntrophin
UniProt Synonym Protein Names
59 kDa dystrophin-associated protein A1 basic component 2; Syntrophin-3; SNT3; Syntrophin-like; SNTL
Protein Family
Beta-2-syntrophin
UniProt Gene Name
Sntb2
UniProt Synonym Gene Names
Snt2b2; SNT3; SNTL
UniProt Entry Name
SNTB2_MOUSE
NCBI Protein Information
beta-2-syntrophin

UniProt Comments for SNTB2

SNTB2: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN. Monomer and homodimer (Probable). Interacts with the other members of the syntrophin family: SNTA1 and SNTB1; and with the sodium channel proteins SCN4A and SCN5A. Interacts with SAST, MAST205, microtubules and microtubule-associated proteins. Interacts with the dystrophin protein DMD and related proteins DTNA and UTRN, and with the neuroregulin receptor ERBB4. Interacts with PTPRN when phosphorylated, protecting PTPRN from protein cleavage by CAPN1. Dephosphorylation upon insulin stimulation disrupts the interaction with PTPRN and results in the cleavage of PTPRN. Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed. Belongs to the syntrophin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Adaptor/scaffold; Dystrophin complex

Cellular Component: microtubule; focal adhesion; protein complex; cytoskeleton; membrane; cytoplasm; synapse; cytoplasmic vesicle; cell junction

Molecular Function: calmodulin binding; protein binding; actin binding
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Research Articles on SNTB2

1. ICA512-CCF also dimerizes with intact ICA512 on granules, thereby displacing it from beta2-syntrophin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SNTB2 antibody

 Products by Pathway  Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with anti-SNTB2 antibody

 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >1 publications with SNTB2 and Atherosclerosis
 Liver Diseases Antibodies  >1 publications with SNTB2 and Liver Diseases
 Adenocarcinoma Antibodies  >1 publications with SNTB2 and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with SNTB2 and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with SNTB2 and Lung Neoplasms

Organs/Tissues associated with anti-SNTB2 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with SNTB2 and Lung
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