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14.3.3 eta Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS836162

MBS836162 is a recombinant protein targeting 14.3.3 eta. Also known as 14.3.3 eta protein (His tag). Host: E. coli. More details

$720 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
14.3.3 eta, Recombinant Protein
Full Product Name
14.3.3 eta protein (His tag)
Product Gene Name
14.3.3 eta recombinant protein
Product Synonym Names
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein protein; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide protein; Protein AS1 protein; YWHAH protein; 14.3.3 eta; YWHA 1.; HGNC:12853 protein; YWHA1 protein; 14-3-3 eta protein; eta polypeptide 14 3 3 protein eta protein; 14-3-3 eta; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide protein; eta polypeptide protein; 14/3/3 eta protein; 14/3/3 eta
Host
E. coli
Form/Format
0.2um filtered liquid in 20mM Tris-HCI, pH 8.0 with 10% glycerol.
Purity/Purification
> 95% pure
Concentration
1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4°C for short term.
Long term: -20°C
Molecular Weight
30.3 kDa (266 aa)
OMIM
113508
3D Structure
ModBase 3D Structure for Q04917
Grade
Recombinant
Tag/Conjugate
His tag
Biohazard
Not hazardous. Use normal laboratory precautions when handling.

Product Categories/Family for 14.3.3 eta recombinant protein

Signal Transduction; Conjugated Proteins
Applications Tested/Suitable for 14.3.3 eta recombinant protein
SDS-PAGE
Application Notes for 14.3.3 eta recombinant protein
14.3.3 eta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Other Notes

Small volumes of 14.3.3 eta recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for 14.3.3 eta. It may not necessarily be applicable to this product.

NCBI GI #
4507951
NCBI GeneID
7533
NCBI Accession #
NP_003396.1
UniProt Primary Accession #
Q04917
UniProt Related Accession #
Q04917
GenBank Nucleotide #
NM_003405.3
NCBI Official Full Name
14-3-3 protein eta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
NCBI Official Symbol
YWHAH
NCBI Official Synonym Symbols
YWHA1
UniProt Protein Name
14-3-3 protein eta
UniProt Synonym Protein Names
Protein AS1
Protein Family
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
UniProt Gene Name
YWHAH
UniProt Synonym Gene Names
YWHA1
UniProt Entry Name
1433F_HUMAN
NCBI Protein Information
14-3-3 protein eta

NCBI Summary for 14.3.3 eta

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]
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UniProt Comments for 14.3.3 eta

14-3-3 eta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.

Protein type: Adaptor/scaffold; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: cytoplasmic vesicle membrane; cytoplasm; plasma membrane; cytosol

Molecular Function: insulin-like growth factor receptor binding; protein domain specific binding; protein binding; enzyme binding; sodium channel regulator activity; protein heterodimerization activity; actin binding; glucocorticoid receptor binding

Biological Process: intracellular protein transport; substantia nigra development; apoptosis; regulation of neuron differentiation; positive regulation of transcription, DNA-dependent; glucocorticoid receptor signaling pathway; regulation of synaptic plasticity; glucocorticoid catabolic process; negative regulation of dendrite morphogenesis; regulation of sodium ion transport
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Research Articles on 14.3.3 eta

1. This study identified YWHAH significantly associated loci with a biologically plausible role in schizophrenia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with 14.3.3 eta recombinant protein

 Reference Product  PubMed Publications
 YWHAE recombinant protein  >2 publications with 14.3.3 eta and YWHAE
 FOXO3 recombinant protein  >1 publications with 14.3.3 eta and FOXO3
 CDC25C recombinant protein  >1 publications with 14.3.3 eta and CDC25C
 CDC25B recombinant protein  >1 publications with 14.3.3 eta and CDC25B

Pathways associated with 14.3.3 eta recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram

Diseases associated with 14.3.3 eta recombinant protein

 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >1 publications with 14.3.3 eta and Insulin Resistance
 Carcinoma, Hepatocellular Antibodies  >1 publications with 14.3.3 eta and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with 14.3.3 eta and Liver Diseases
 Neoplasms, Experimental Antibodies  >1 publications with 14.3.3 eta and Neoplasms, Experimental
 Hypertrophy Antibodies  >1 publications with 14.3.3 eta and Hypertrophy
 Liver Neoplasms Antibodies  >1 publications with 14.3.3 eta and Liver Neoplasms
 Hyperplasia Antibodies  >1 publications with 14.3.3 eta and Hyperplasia

Organs/Tissues associated with 14.3.3 eta recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with 14.3.3 eta and Brain
 Blood Antibodies  >3 publications with 14.3.3 eta and Blood
 Bone Antibodies  >3 publications with 14.3.3 eta and Bone
 Liver Antibodies  >2 publications with 14.3.3 eta and Liver
 Bone Marrow Antibodies  >2 publications with 14.3.3 eta and Bone Marrow
 Heart Antibodies  >1 publications with 14.3.3 eta and Heart
 Vascular Antibodies  >1 publications with 14.3.3 eta and Vascular
 Lymph Antibodies  >1 publications with 14.3.3 eta and Lymph
 Eye Antibodies  >1 publications with 14.3.3 eta and Eye
 Lung Antibodies  >1 publications with 14.3.3 eta and Lung
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