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Coronin 1b (CORO1B) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS837505

MBS837505 is an antibody targeting CORO1B. Also known as Coronin 1B antibody. Host: Rabbit. Affinity purified Rabbit polyclonal Coronin 1B antibody More details

$1575 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Coronin 1B (CORO1B), Polyclonal Antibody
Full Product Name
Coronin 1B antibody
Product Gene Name
anti-CORO1B antibody
Product Synonym Names
Polyclonal Coronin 1B; Anti-Coronin 1B; coronin-1B; Coronin B-1; CORO1B; Coronin B 1; coronin actin binding protein 1B; CORONIN-2; Coronin 1B; DKFZp762I166
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Purity/Purification
Coronin 1B antibody was purified by antigen-affinity chromatography
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
54 kDa
OMIM
609849
3D Structure
ModBase 3D Structure for Q9BR76
Cross-Reactivity
Human, Mouse
Immunogen
Coronin 1B antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 173  of Coronin 1B

Product Categories/Family for anti-CORO1B antibody

Cell Biology; Purified Polyclonal Antibodies
Applications Tested/Suitable for anti-CORO1B antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-CORO1B antibody
IHC-P: 1:100-1:500
WB: 1:500-1:3000

Western Blot (WB) of anti-CORO1B antibody

Western blot analysis of 30 ug of whole cell lysate (A: NIH-3T3) using a 10 % SDS PAGE gel and Coronin 1B antibody at a dilution of 1:1000
Rabbit Anti-CORO1B Polyclonal Antibody – Cat# MBS837505

Western Blot (WB) of anti-CORO1B antibody

Western blot analysis of 30 ug whole cell lysate (A:293T) using a 10 % SDS PAGE gel and Coronin 1B antibody at a dilution of 1:1000
Rabbit Anti-CORO1B Polyclonal Antibody, Western Blot (WB) – Cat# MBS837505

Immunohistochemistry (IHC) of anti-CORO1B antibody

Immunohistochemical staining of paraffin-embedded H1299 xenograft using Coronin 1B antibody at a dilution of 1:500
Rabbit Anti-CORO1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS837505

Other Notes

Small volumes of anti-CORO1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CORO1B. It may not necessarily be applicable to this product.

NCBI GI #
65787364
NCBI GeneID
57175
NCBI Accession #
NP_001018080.1
UniProt Primary Accession #
Q9BR76
UniProt Secondary Accession #
B2RD45
UniProt Related Accession #
Q9BR76
GenBank Nucleotide #
NM_001018070.2
NCBI Official Full Name
coronin-1B
NCBI Official Synonym Full Names
coronin, actin binding protein, 1B
NCBI Official Symbol
CORO1B
NCBI Official Synonym Symbols
CORONIN-2
UniProt Protein Name
Coronin-1B
UniProt Synonym Protein Names
Coronin-2
Protein Family
Coronin
UniProt Gene Name
CORO1B
UniProt Entry Name
COR1B_HUMAN
NCBI Protein Information
coronin-1B

NCBI Summary for CORO1B

Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]

UniProt Comments for CORO1B

coronin 1B: an actin-binding protein that regulates leading edge dynamics and cell motility in fibroblasts. Coordinates the Arp2/3 complex (includes ACTR2, ARPC1B and ARPC2) cofilin activities at the leading edge. Localized to the leading edge in fibroblasts and weakly along actin stress fibers. Phosphorylation by PKC regulates the interaction with the Arp2/3 complex and cell motility in fibroblasts. Belongs to the WD repeat coronin family.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: focal adhesion; lamellipodium; leading edge; cytoplasm; stress fiber; plasma membrane; actin filament; actin cytoskeleton

Molecular Function: actin filament binding; identical protein binding; protein binding

Biological Process: actin filament bundle formation; cell migration; wound healing; ruffle organization and biogenesis; actin cytoskeleton organization and biogenesis
Show more

Research Articles on CORO1B

1. Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CORO1B antibody

 Reference Product  PubMed Publications
 ACTB antibody  >1 publications with CORO1B and ACTB

Diseases associated with anti-CORO1B antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >1 publications with CORO1B and Death
 Vascular Diseases Antibodies  >1 publications with CORO1B and Vascular Diseases

Organs/Tissues associated with anti-CORO1B antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with CORO1B and Vascular
 Bone Marrow Antibodies  >1 publications with CORO1B and Bone Marrow
 Bone Antibodies  >1 publications with CORO1B and Bone
 Embryonic Tissue Antibodies  >1 publications with CORO1B and Embryonic Tissue
 Blood Antibodies  >1 publications with CORO1B and Blood
 Stomach Antibodies  >1 publications with CORO1B and Stomach
 Heart Antibodies  >1 publications with CORO1B and Heart
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