• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Coilin (COIL) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS837878

MBS837878 is an antibody targeting COIL. Also known as Coilin antibody. Host: Mouse. Mouse monoclonal Coilin antibody More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Coilin, Monoclonal Antibody
Full Product Name
Coilin antibody
Product Gene Name
Product Synonym Names
Monoclonal Coilin; Anti-Coilin; COIL; coilin; BOS_18308; C79982; CG8710-PC; CG8710-PD; CH211-234H8.8; CLN80; coilin p80; coil-PC; coil-PD; dcoilin; Dmel_CG8710; nuclear phosphoprotein of Cajal body; p80; p80-coilin; RP23-176J13.5; sph1; sphere organelle protein sph-1; sphere organelles protein SPH-1; sphere protein 1
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
1H10
Host
Mouse
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
Molecular Weight
62,608 Da
OMIM
600272
Cross-Reactivity
Human
Immunogen
Coilin antibody was raised in Mouse using a recombinant human protein purified from E Coli (His-Coilin) as the immunogen

Product Categories/Family for anti-COIL antibody

Applications Tested/Suitable for anti-COIL antibody
Western Blot (WB)
Application Notes for anti-COIL antibody
WB: 1:2000

Western Blot (WB) of anti-COIL antibody

Mouse Anti-COIL Monoclonal Antibody – Cat# MBS837878

Other Notes

Small volumes of anti-COIL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for COIL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
coilin
NCBI Official Synonym Full Names
coilin
NCBI Official Symbol
COIL
NCBI Official Synonym Symbols
CLN80; p80-coilin
UniProt Protein Name
Coilin
UniProt Synonym Protein Names
p80-coilin
Protein Family
UniProt Gene Name
COIL
UniProt Synonym Gene Names
CLN80
UniProt Entry Name
COIL_HUMAN
NCBI Protein Information
coilin

NCBI Summary for COIL

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for COIL

coilin: an ubiquitous protein found in nuclear coiled bodies (CBS), nuclear suborganelles involved in the post-transcriptional modification of snRNPs and small nucleolar RNAs. snRNPs undergo 2'-O-methylation and pseudouridylation in CBS. Differential methylation and phosphorylation of coilin likely influences localization among nuclear bodies and the composition and assembly of CBS. Located in the interchromatin space between the nucleolus and the nucleus.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: nucleoplasm; Cajal body; membrane; cytoplasm; nucleolus; nucleus

Molecular Function: protein C-terminus binding; identical protein binding; protein binding
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000