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Luteinizing Hormone Beta (LHB) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS838284

Luteinizing hormone (LH) is a hormone produced by the anterior pituitary gland. In females, an acute rise of LH called the LH surge triggers ovulation and development of the corpus luteum. In males, where LH had also been called interstitial cell-stimulating… More details

$350 / 1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Luteinizing Hormone beta (LHB), Monoclonal Antibody
Full Product Name
Luteinizing Hormone beta antibody
Product Gene Name
Product Synonym Names
Monoclonal Luteinizing Hormone beta; Anti-Luteinizing Hormone beta; Luteinizing Hormone-beta
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M1709LH
Host
Mouse
Species Reactivity
Specific for LH β subunit. Negative for alpha subunit of LH, HCG, and for both alpha and beta subunit of TSH and FSH.
Form/Format
Liquid in 50mM NaCl, 10 mM PBS, pH 8.0 with 0.1% NaN3
Purity/Purification
> 95% pure
Concentration
24.05 mg/ml (lot specific)
Specificity
Beta-subunit of LH
Preparation and Storage
Store at 4°C for short term storage, -20°C for long term.
Matching Pairs
Capture Antibody: Luteinizing Hormone alpha Clone #M1709LHa (MBS838600)
Detection Antibody: Luteinizing Hormone beta Clone #M1709LH (MBS838284)
Comments: Suitable for use in ELISA & Lateral Flow to detect LH
OMIM
152780
Immunogen
Luteinizing Hormone β antibody was raised in Mouse using LH as the immunogen

Product Categories/Family for anti-LHB antibody

Applications Tested/Suitable for anti-LHB antibody
ELISA (EIA) or Lateral Flow immunoassay (double antibody test for LH detection).
Application Notes for anti-LHB antibody
This antibody can be used as the labelling antibody with MBS838600 as the coating antibody to detect LH.

Other Notes

Small volumes of anti-LHB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LHB purchase

MBS838284 is an antibody targeting LHB. Also known as Luteinizing Hormone beta antibody. Reactive in Specific for LH β subunit. Negative for alpha subunit of LH, HCG, and for both alpha and beta subunit of TSH and FSH.. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LHB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
luteinizing hormone beta subunit (LHbeta), partial
NCBI Official Synonym Full Names
luteinizing hormone beta polypeptide
NCBI Official Symbol
LHB
NCBI Official Synonym Symbols
CGB4; HH23; hLHB; LSH-B
UniProt Protein Name
Lutropin subunit beta
UniProt Synonym Protein Names
Luteinizing hormone subunit beta; LH-B; LSH-B; LSH-beta
UniProt Gene Name
LHB
UniProt Synonym Gene Names
Lutropin beta chain; LH-B; LSH-B; LSH-beta
UniProt Entry Name
LSHB_HUMAN
NCBI Protein Information
lutropin subunit beta

NCBI Summary for LHB

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
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UniProt Comments for LHB

LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Secreted; Hormone; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity; receptor binding

Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction

Disease: Fertile Eunuch Syndrome
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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