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PRKD2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS838290

MBS838290 is an antibody targeting PRKD2. Also known as PRKD2 antibody. Host: Mouse. Mouse monoclonal PRKD2 antibody More details

$1625 / 0.1 mL +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRKD2, Monoclonal Antibody
Full Product Name
PRKD2 antibody
Product Gene Name
anti-PRKD2 antibody
Product Synonym Names
Monoclonal PRKD2; Anti-PRKD2; Protein kinase D2; PKD2; DKFZP586E0820; HSPC187; PRKD2; PRKD 2; PRKD-2
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
3A1
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
PRKD2 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
80,143 Da
OMIM
607074
Cross-Reactivity
Human
Immunogen
PRKD2 antibody was raised in mouse using a full length recombinant protein of human PRKD2 (NP_057541) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-PRKD2 antibody

Proteases; Inhibitors; & Enzymes
Applications Tested/Suitable for anti-PRKD2 antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-PRKD2 antibody
FC: 1:100
WB: 1:2000

Flow Cytometry (FC/FACS) of anti-PRKD2 antibody

Flow Cytometric analysis of HEK293T cells transfected with either recombinant PRKD2 protein (red) or empty vector (blue) stained using PRKD2 antibody
Mouse Anti-PRKD2 Monoclonal Antibody – Cat# MBS838290

Western Blot (WB) of anti-PRKD2 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PRKD2 protein (Right) or empty vector (Left) detected with PRKD2 antibody
Mouse Anti-PRKD2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS838290

Other Notes

Small volumes of anti-PRKD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRKD2. It may not necessarily be applicable to this product.

NCBI GI #
117938781
NCBI GeneID
25865
NCBI Accession #
AAH15472.1
UniProt Secondary Accession #
Q8NCK8; Q8TB08; Q9P0T6; Q9Y3X8; M0R2R2
UniProt Related Accession #
Q9BZL6
NCBI Official Full Name
PRKD2 protein, partial
NCBI Official Synonym Full Names
protein kinase D2
NCBI Official Symbol
PRKD2
NCBI Official Synonym Symbols
PKD2; HSPC187; nPKC-D2
UniProt Protein Name
Serine/threonine-protein kinase D2
UniProt Synonym Protein Names
nPKC-D2
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
PRKD2
UniProt Synonym Gene Names
PKD2
UniProt Entry Name
KPCD2_HUMAN
NCBI Protein Information
serine/threonine-protein kinase D2

NCBI Summary for PRKD2

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for PRKD2

PRKD2: a calcium-independent, phospholipid-dependent CAMK kinase of the PKD family. Activated by diacylglycerol and phorbol esters. may play a role in carcinoid tumor progression.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.13; Protein kinase, CAMK; Kinase, protein; Motility/polarity/chemotaxis; CAMK group; PKD family

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; protein kinase C activity; metal ion binding; ATP binding; protein kinase activity

Biological Process: cell death; positive regulation of cell adhesion; protein amino acid autophosphorylation; positive regulation of blood vessel endothelial cell migration; activation of CREB transcription factor; positive regulation of fibroblast growth factor receptor signaling pathway; protein amino acid phosphorylation; positive regulation of peptidyl-serine phosphorylation; T cell receptor signaling pathway; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; peptidyl-serine phosphorylation; positive regulation of angiogenesis; positive regulation of T cell receptor signaling pathway; positive regulation of interleukin-2 production; positive regulation of transcription factor activity; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; vascular endothelial growth factor receptor signaling pathway; cell adhesion
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Research Articles on PRKD2

1. Loss of PKD2 enhanced KC proliferative potential while loss of PKD3 resulted in a progressive proliferation defect, loss of clonogenicity and diminished tissue regenerative ability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PRKD2 antibody

 Products by Pathway  Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram

Diseases associated with anti-PRKD2 antibody

 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >2 publications with PRKD2 and Skin Diseases
 Immune System Diseases Antibodies  >2 publications with PRKD2 and Immune System Diseases
 Gastrointestinal Diseases Antibodies  >1 publications with PRKD2 and Gastrointestinal Diseases
 Kidney Diseases Antibodies  >1 publications with PRKD2 and Kidney Diseases
 Nervous System Diseases Antibodies  >1 publications with PRKD2 and Nervous System Diseases
 Diabetes Mellitus Antibodies  >1 publications with PRKD2 and Diabetes Mellitus
 Inflammation Antibodies  >1 publications with PRKD2 and Inflammation
 Leukemia, Lymphocytic, Chronic, B-Cell Antibodies  >1 publications with PRKD2 and Leukemia, Lymphocytic, Chronic, B-Cell

Organs/Tissues associated with anti-PRKD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with PRKD2 and Blood
 Vascular Antibodies  >2 publications with PRKD2 and Vascular
 Bone Antibodies  >1 publications with PRKD2 and Bone
 Mouth Antibodies  >1 publications with PRKD2 and Mouth
 Bone Marrow Antibodies  >1 publications with PRKD2 and Bone Marrow
 Brain Antibodies  >1 publications with PRKD2 and Brain
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