• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RDH11 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS838636

MBS838636 is an antibody targeting RDH11. Also known as RDH11 antibody. Host: Mouse. Mouse monoclonal RDH11 antibody More details

$1615 / 0.1 mL +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RDH11, Monoclonal Antibody
Full Product Name
RDH11 antibody
Product Gene Name
anti-RDH11 antibody
Product Synonym Names
Monoclonal RDH11; Anti-RDH11; Retinol Dehydrogenase 11; All-Trans/9-Cis/11-Cis; ARSDR1; CGI-82; FLJ32633; HCBP12; MDT1; PSDR1; RALR1; SCALD; RDH11; RDH 11; RDH-11
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1B4
Host
Mouse
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purity/Purification
RDH11 antibody was purified by affinity chromatography.
Concentration
500 ug-1 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight
27,402 Da
OMIM
607849
Cross-Reactivity
Human
Immunogen
RDH11 antibody was raised in mouse using a full length recombinant protein of human RDH11 (NP_057110) produced in HEK293T cells, as the immunogen.

Product Categories/Family for anti-RDH11 antibody

Nutrition & Metabolism
Applications Tested/Suitable for anti-RDH11 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-RDH11 antibody
FC: 1:100
IF: 1:100
IHC: 1:50
WB: 1:2000

Flow Cytometry (FC/FACS) of anti-RDH11 antibody

Flow Cytometric analysis of HEK293T cells transfected with either recombinant RDH11 protein (red) or empty vector (blue) stained using RDH11 antibody
Mouse Anti-RDH11 Monoclonal Antibody – Cat# MBS838636

Western Blot (WB) of anti-RDH11 antibody

Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant RDH11 protein (Right) or empty vector (Left) detected with RDH11 antibody
Mouse Anti-RDH11 Monoclonal Antibody, Western Blot (WB) – Cat# MBS838636

Immunohistochemistry (IHC) of anti-RDH11 antibody

Immunohistochemical analysis of RDH11 protein in paraffin embedded Carcinoma of Human liver tissue using RDH11 antibody
Mouse Anti-RDH11 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS838636

Immunofluorescence (IF) of anti-RDH11 antibody

Immunofluorescent staining of COS7 cells transiently transfected with recombinant RDH11 protein using RDH11 antibody
Mouse Anti-RDH11 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS838636

Other Notes

Small volumes of anti-RDH11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RDH11. It may not necessarily be applicable to this product.

NCBI GI #
358001101
NCBI GeneID
51109
NCBI Accession #
NP_001239579.1
UniProt Secondary Accession #
Q0QD40; Q6IAH5; Q9NRW0; Q9Y391; A6NDK3; A8K062; B2RB26; B4DDW0
UniProt Related Accession #
Q8TC12
GenBank Nucleotide #
NM_001252650.1
NCBI Official Full Name
retinol dehydrogenase 11 isoform 2
NCBI Official Synonym Full Names
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
NCBI Official Symbol
RDH11
NCBI Official Synonym Symbols
MDT1; CGI82; PSDR1; RALR1; SCALD; ARSDR1; HCBP12; RDJCSS; SDR7C1
UniProt Protein Name
Retinol dehydrogenase 11
UniProt Synonym Protein Names
Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1; RalR1; Short chain dehydrogenase/reductase family 7C member 1
Protein Family
Retinol dehydrogenase
UniProt Gene Name
RDH11
UniProt Synonym Gene Names
ARSDR1; PSDR1; SDR7C1; RalR1
UniProt Entry Name
RDH11_HUMAN
NCBI Protein Information
retinol dehydrogenase 11

NCBI Summary for RDH11

The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]

UniProt Comments for RDH11

RDH11: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.300; Oxidoreductase

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: endoplasmic reticulum membrane; photoreceptor inner segment; integral to membrane; intracellular

Molecular Function: retinol dehydrogenase activity

Biological Process: phototransduction, visible light; retinal metabolic process; retinol metabolic process; adaptation of rhodopsin mediated signaling; retinoid metabolic process

Disease: Retinal Dystrophy, Juvenile Cataracts, And Short Stature Syndrome
Show more

Research Articles on RDH11

1. deleterious mutations in RDH11, an important enzyme for vision-related and systemic retinoic acid metabolism, cause a new syndrome with RP.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RDH11 antibody

 Reference Product  PubMed Publications
 RPE65 antibody  >2 publications with RDH11 and RPE65
 RDH8 antibody  >2 publications with RDH11 and RDH8
 RDH10 antibody  >1 publications with RDH11 and RDH10
 RBP1 antibody  >1 publications with RDH11 and RBP1
 RBP2 antibody  >1 publications with RDH11 and RBP2

Pathways associated with anti-RDH11 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Retinoic Acid Pathway antibodies  Signaling By Retinoic Acid Pathway Diagram
 The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway antibodies  The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway Diagram
 Visual Phototransduction Pathway antibodies  Visual Phototransduction Pathway Diagram
 Retinol Biosynthesis Pathway antibodies  Retinol Biosynthesis Pathway Diagram

Diseases associated with anti-RDH11 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with RDH11 and Disease Models, Animal
 Prostatic Diseases Antibodies  >2 publications with RDH11 and Prostatic Diseases
 Skin Diseases Antibodies  >1 publications with RDH11 and Skin Diseases
 Breast Neoplasms Antibodies  >1 publications with RDH11 and Breast Neoplasms

Organs/Tissues associated with anti-RDH11 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >11 publications with RDH11 and Eye
 Prostate Antibodies  >4 publications with RDH11 and Prostate
 Liver Antibodies  >2 publications with RDH11 and Liver
 Testis Antibodies  >2 publications with RDH11 and Testis
 Blood Antibodies  >1 publications with RDH11 and Blood
 Intestine Antibodies  >1 publications with RDH11 and Intestine
 Skin Antibodies  >1 publications with RDH11 and Skin
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000