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SLC6A11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS838813

MBS838813 is an antibody targeting SLC6A11. Also known as SLC6A11 antibody. Host: Rabbit. Rabbit polyclonal SLC6A11 antibody More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SLC6A11, Polyclonal Antibody
Full Product Name
SLC6A11 antibody
Product Gene Name
Product Synonym Names
Polyclonal SLC6A11; Anti-SLC6A11; SLC6A 11; SLC6A-11; SLC6A11; Solute carrier family 6 member 11; GAT3
Clonality
Polyclonal
Host
Rabbit
Form/Format
Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol
Purity/Purification
SLC6A11 antibody was purified by affinity chromatography
Molecular Weight
23,036 Da
OMIM
607952
Applications Tested/Suitable for anti-SLC6A11 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC6A11 antibody
WB: 1:1000
IHC: 1:100-1:200

Western Blot (WB) of anti-SLC6A11 antibody

Western blot of rat hippocampal homogenate showing specific immunolabeling of ~ 67k GAT3 protein
Rabbit Anti-SLC6A11 Polyclonal Antibody – Cat# MBS838813

Other Notes

Small volumes of anti-SLC6A11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC6A11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SLC6A11 protein
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter), member 11
NCBI Official Symbol
SLC6A11
NCBI Official Synonym Symbols
GAT3; GAT4; GAT-3
UniProt Protein Name
Sodium- and chloride-dependent GABA transporter 3
UniProt Synonym Protein Names
Solute carrier family 6 member 11
UniProt Gene Name
SLC6A11
UniProt Synonym Gene Names
GABT3; GAT3; GAT-3
UniProt Entry Name
S6A11_HUMAN
NCBI Protein Information
sodium- and chloride-dependent GABA transporter 3

NCBI Summary for SLC6A11

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010]
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UniProt Comments for SLC6A11

SLC6A11: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: cell projection; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane

Molecular Function: neurotransmitter binding; gamma-aminobutyric acid:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: response to drug; synaptic transmission; neurotransmitter secretion; brain development; transmembrane transport; gamma-aminobutyric acid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC6A11 antibody

 Reference Product  PubMed Publications
 SLC1A3 antibody  >1 publications with SLC6A11 and SLC1A3
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