Rabbit Anti-EFNB1 Polyclonal Antibody – Cat# MBS839478

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Ephrin B1/B2 (Phospho-Tyr329) antibody.

Ephrin B1/B2 (EFNB1) Antibody – Rabbit Polyclonal

Name: EFNB1 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS839478
Price: 685 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS839478

MBS839478 is an antibody targeting Efnb1. Also known as Ephrin B1/B2 antibody (Tyr329). Host: Rabbit. Rabbit polyclonal Ephrin B1/B2 antibody (Tyr329) More details

$685 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ephrin B1/B2 (Efnb1), Polyclonal Antibody

Full Product Name

Ephrin B1/B2 antibody (Tyr329)

Product Gene Name

anti-Efnb1 antibody

Product Synonym Names

Polyclonal Ephrin B1/B2; Anti-Ephrin B1/B2; CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; EFL-3; EFNB1; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; EPL2; EPLG2; Ephrin-B1 precursor; LERK-2; LERK2; STRA1; STRA1protein; kinaseephrin-B1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Form/Format

Supplied in PBS buffer (without Mg2+and Ca2+), pH 7.4, 150mM NaCl with 0.02% sodium azide and 50% glycerol

Concentration

1 mg/ml (lot specific)

Specificity

Ephrin B1/B2 antibody detects endogenous levels of Ephrin B1/B2 only when phosphorylated at tyrosine 329

Preparation and Storage

Aliquot and store at -20 degree C. Avoid repeated freeze thaw cycles

Molecular Weight

37,951 Da

Cross-Reactivity

Mouse, Rat

Immunogen

Ephrin B1/B2 antibody was raised in Rabbit using synthesized phosphopeptide derived from human Ephrin B1/B2 around the phosphorylation site of tyrosine 329 (P-V-YP-I-V) as the immunogen

Product Categories/Family for anti-Efnb1 antibody

Signal Transduction; Purified Polyclonal Antibodies

Applications Tested/Suitable for anti-Efnb1 antibody

Immunohistochemistry (IHC), ELISA (EIA)

Application Notes for anti-Efnb1 antibody

IHC: 1:50-1:100
ELISA: 1:10000

Other Notes

Small volumes of anti-Efnb1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Efnb1. It may not necessarily be applicable to this product.

NCBI GI #

40254779

NCBI GeneID

25186

NCBI Accession #

NP_058785.2

UniProt Related Accession #

P52796

GenBank Nucleotide #

NM_017089.2

NCBI Official Full Name

ephrin-B1

NCBI Official Synonym Full Names

ephrin B1

NCBI Official Symbol

Efnb1

NCBI Official Synonym Symbols

LERK2

UniProt Protein Name

Ephrin-B1

UniProt Synonym Protein Names

ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2

Protein Family

Ephrin

UniProt Gene Name

Efnb1

UniProt Synonym Gene Names

Eplg2; Lerk2; ELK-L; LERK-2

UniProt Entry Name

EFNB1_RAT

NCBI Protein Information

ephrin-B1

NCBI Summary for Efnb1

induces neurite outgrowth; may play a role in positive regulation of cerebellar development [RGD, Feb 2006]

UniProt Comments for Efnb1

EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

Protein type: Ligand, receptor tyrosine kinase; Membrane protein, integral

Cellular Component: cytoplasm; plasma membrane; integral to membrane; synapse; nucleus; lipid raft

Molecular Function: protein binding; ephrin receptor binding

Biological Process: nervous system development; axon guidance; ephrin receptor signaling pathway; positive regulation of T cell proliferation; embryonic pattern specification; neural crest cell migration

Research Articles on Efnb1

1. The EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Efnb1 antibody

Reference Product	PubMed Publications
Ephb2 antibody	>15 publications with Efnb1 and Ephb2
Ephb1 antibody	>11 publications with Efnb1 and Ephb1
Ephb4 antibody	>7 publications with Efnb1 and Ephb4
Epha2 antibody	>5 publications with Efnb1 and Epha2
Ephb3 antibody	>4 publications with Efnb1 and Ephb3
Epha4 antibody	>3 publications with Efnb1 and Epha4
Ephb6 antibody	>3 publications with Efnb1 and Ephb6
Epha1 antibody	>1 publications with Efnb1 and Epha1
Rgs3 antibody	>1 publications with Efnb1 and Rgs3

Pathways associated with anti-Efnb1 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPH-Ephrin Signaling Pathway antibodies	EPH-Ephrin Signaling Pathway Diagram
EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies	EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
EPHB-mediated Forward Signaling Pathway antibodies	EPHB-mediated Forward Signaling Pathway Diagram
Ephrin Signaling Pathway antibodies	Ephrin Signaling Pathway Diagram

Organs/Tissues associated with anti-Efnb1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>22 publications with Efnb1 and Brain
Embryonic Tissue Antibodies	>8 publications with Efnb1 and Embryonic Tissue
Connective Tissue Antibodies	>4 publications with Efnb1 and Connective Tissue
Eye Antibodies	>4 publications with Efnb1 and Eye
Spleen Antibodies	>3 publications with Efnb1 and Spleen
Ovary Antibodies	>2 publications with Efnb1 and Ovary
Kidney Antibodies	>2 publications with Efnb1 and Kidney
Adipose Tissue Antibodies	>1 publications with Efnb1 and Adipose Tissue
Heart Antibodies	>1 publications with Efnb1 and Heart
Prostate Antibodies	>1 publications with Efnb1 and Prostate