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Troleandomycin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400334

Troleandomycin is a macrolide antibiotic similar to erythromycin . Inhibits cytochrome P450 (IC50 = 0-5uM), thus blocking CYP450-dependent drug oxidation. It binds to the 50S subunit of the bacterial ribosome. This binding inhibits translocation of tRNA along… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Troleandomycin, Biochemical
Full Product Name
Troleandomycin
Product Synonym Names
[(3R, 5S, 6S, 7R, 8S, 9R, 12R, 13S, 14S, 15R)-6-[(2S, 3R, 4S, 6R)-3-acetyloxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-8-[(2R, 4S, 5S, 6S)-5-acetyloxy-4-methoxy-6-methyloxan-2-yl]oxy-5, 7, 9, 12, 13, 15-hexamethyl-10, 16-dioxo-1, 11-dioxaspiro[2.13]hexadecan-14-yl] acetate
Form/Format
White solid
Purity/Purification
>=98%
Specificity
A macrolide antibiotic
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
813.99
Solubilities
~25mg/ml Ethanol; ~50mg/ml DMSO
Molecular Formula
C??H??NO??
InChi
InChI=1S/C41H67NO15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26; 30-37; 40H; 15-18H2; 1-14H3/t19-; 20+; 21-; 22+; 23+; 24+; 25+; 26-; 30-; 31-; 32-; 33-; 34-; 35-; 36-; 37+; 40-; 41+/m0/s1
InChi Key
LQCLVBQBTUVCEQ-QTFUVMRISA-N
SMILES
CC1CC(C(C(O1)OC2C(CC3(CO3)C(=O)C(C(C(C(OC(=O)C(C(C2C)OC4CC(C(C(O4)C)OC(=O)C)OC)C)C)C)OC(=O)C)C)C)OC(=O)C)N(C)C
CAS Number
311074
MDL Number
MFCD00871198
PubChem CID
202225

Product Categories/Family for Troleandomycin biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z); Drug Metabolism and Disposition; CYP inhibitors-inactivators; Antibiotics

Structure of Troleandomycin biochemical

Troleandomycin Biochemical – Cat# MBS8400334

Product References and Citations for Troleandomycin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/Troleandomycin

Other Notes

Small volumes of Troleandomycin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Troleandomycin purchase

MBS8400334 is a biochemical targeting Troleandomycin.
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