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Merimepodib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400345

Merimepodib (VX-497) is a novel noncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH). Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Merimepodib, Biochemical
Full Product Name
Merimepodib
Product Synonym Names
(3S)-oxolan-3-yl N-{[3-({[3-methoxy-4-(1, 3-oxazol-5-yl)phenyl]carbamoyl}amino)phenyl]methyl}carbamate, VX-497, VX497
Form/Format
Crystalline solid
Purity/Purification
>=98%
Specificity
A novel noncompetitive IMPDH inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
452.46
Solubilities
~30mg/ml DMSO
Molecular Formula
C??H??N?O?
InChi
InChI=1S/C23H24N4O6/c1-30-20-10-17(5-6-19(20)21-12-24-14-32-21)27-22(28)26-16-4-2-3-15(9-16)11-25-23(29)33-18-7-8-31-13-18/h2-6; 9-10; 12; 14; 18H; 7-8; 11; 13H2; 1H3; (H; 25; 29)(H2; 26; 27; 28)/t18-/m0/s1
InChi Key
JBPUGFODGPKTDW-SFHVURJKSA-N
SMILES
O=C(O[C@@H]1COCC1)NCC2=CC=CC(NC(NC3=CC=C(C4=CN=CO4)C(OC)=C3)=O)=C2
CAS Number
198821-22-6
PubChem CID
153241

Product Categories/Family for Merimepodib biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Merimepodib biochemical

Merimepodib Biochemical – Cat# MBS8400345

Product References and Citations for Merimepodib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/153241

Other Notes

Small volumes of Merimepodib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Merimepodib purchase

MBS8400345 is a biochemical targeting Merimepodib.
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