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Withaferin A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400356

Withaferin A is a steroid lactone that displays potent anti-inflammatory, antitumor and antiangiogenic activity. Inhibits endothelial cells (HUVEC) sprouting in vitro (IC50 = 12nM) and in vivo. Prevents NF-kappaB activation by inhibiting activation of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Withaferin A, Biochemical
Full Product Name
Withaferin A
Product Synonym Names
NSC 101088, 5beta, 6beta-epoxy-4beta, 22R, 27-trihydroxy-1-oxo-delta-lactone-ergosta-2, 24-dien-26-oic acid, NSC 273757
Form/Format
White to off-white or slightly yellow crystalline solid
Purity/Purification
>=98%
Specificity
A steroidal lactone
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
470.6
Solubilities
~ 5mg/ml DMSO
Molecular Formula
C??H??O?
InChi
InChI=1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28; 4)20(16)9-10-26(18; 19)3/h7-8; 15-16; 18-21; 23-24; 29; 31H; 5-6; 9-13H2; 1-4H3/t15-; 16-; 18+; 19-; 20-; 21+; 23-; 24+; 26+; 27-; 28+/m0/s1
InChi Key
DBRXOUCRJQVYJQ-CKNDUULBSA-N
SMILES
CC1=C(C(=O)OC(C1)C(C)C2CCC3C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)CO
CAS Number
5119-48-2
MDL Number
MFCD10687098
PubChem CID
265237

Product Categories/Family for Withaferin A biochemical

Web Categories; Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Angiogenesis Inhibitors; Enzyme Inhibitors (A-Z)

Structure of Withaferin A biochemical

Withaferin A Biochemical – Cat# MBS8400356

Product References and Citations for Withaferin A biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/265237

Other Notes

Small volumes of Withaferin A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Withaferin A purchase

MBS8400356 is a biochemical targeting Withaferin A.
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