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AM-251

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400358

AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8nM. It also acts as an agonist at GPR55 (EC50 = 39nM) and potentiates GABAA receptor currents (EC50 = 0.4uM). In mice, AM251 reduces antidepressant-like behavior in the tail… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AM-251, Biochemical
Full Product Name
AM-251
Product Gene Name
Product Synonym Names
1-(2, 4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide, AM251
Form/Format
White to off-white solid
Purity/Purification
>=98%
Specificity
A selective cannabinoid 1 (CB1) receptor antagonist
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
555.24
Solubilities
>20mg/ml DMSO
Molecular Formula
C??H??Cl?IN?O
InChi
InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10; 13H; 2-4; 11-12H2; 1H3; (H; 27; 30)
InChi Key
BUZAJRPLUGXRAB-UHFFFAOYSA-N
SMILES
Ic1ccc(cc1)c1c(C)c(nn1c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
CAS Number
183232-66-8
MDL Number
MFCD01861181
PubChem CID
2125

Structure of AM-251 biochemical

AM-251 Biochemical – Cat# MBS8400358

Product References and Citations for AM-251 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/2125

Other Notes

Small volumes of AM-251 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AM-251 purchase

MBS8400358 is a biochemical targeting AM-251.

Additional Details

NCBI/Uniprot data below describe general gene information for AM-251. It may not necessarily be applicable to this product.

Protein Family

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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