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Ketoconazole

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400375

Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14alpha-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. Ketoconazole also inhibits… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ketoconazole, Biochemical
Full Product Name
Ketoconazole
Product Synonym Names
Fungoral, 1-[4-[4-[[(2R, 4S)-2-(2, 4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1, 3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Form/Format
Off-white solid
Purity/Purification
>=98%
Specificity
An antifungal agent
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
531.43
Solubilities
~ 2mg/ml DMSO
Molecular Formula
C??H??Cl?N?O?
InChi
InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23; 17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9; 14; 18; 23H; 10-13; 15-17H2; 1H3/t23-; 26-/m0/s1
InChi Key
XMAYWYJOQHXEEK-OZXSUGGESA-N
SMILES
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
CAS Number
65277-42-1
MDL Number
MFCD00058579
PubChem CID
456201

Product Categories/Family for Ketoconazole biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Ketoconazole biochemical

Ketoconazole Biochemical – Cat# MBS8400375

Product References and Citations for Ketoconazole biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/456201

Other Notes

Small volumes of Ketoconazole biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ketoconazole purchase

MBS8400375 is a biochemical targeting Ketoconazole.
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