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IOX3 (FG-2216)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400379

IOX3 (FG-2216) is a potent, orally bioavailable HIF-prolyl hydroxylase (PHD) inhibitor with IC50 of 3.9uM for PDH2 enzyme. It has been shown to reversibly stimulate erythropoietin secretion at 100uM in vitro. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IOX3, Biochemical
Full Product Name
IOX3 (FG-2216)
Product Gene Name
IOX3 biochemical
Product Synonym Names
N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-glycine
Form/Format
Crystalline solid
Purity/Purification
>=98%
Specificity
An orally active PHD2 inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
280.7
Solubilities
~20mg/ml DMSO
Molecular Formula
C??H?ClN?O?
InChi
InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4; 18H; 5H2; (H; 14; 19)(H; 16; 17)
InChi Key
OUQVKRKGTAUJQA-UHFFFAOYSA-N
SMILES
OC1=C(C(NCC(O)=O)=O)N=C(Cl)C2=CC=CC=C21
CAS Number
223387-75-5
PubChem CID
6914666

Product Categories/Family for IOX3 biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; HIF-pHInhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of IOX3 biochemical

IOX3 (FG-2216) Biochemical – Cat# MBS8400379

Product References and Citations for IOX3 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/6914666

Other Notes

Small volumes of IOX3 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IOX3 purchase

MBS8400379 is a biochemical targeting IOX3. Also known as IOX3 (FG-2216).
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