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BAY-1816032

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400390

BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7nM. Displays excellent selectivity over a panel of 395 kinases. BAY 1816032 abrogates nocodazole-induced Thr-120 phosphorylation of the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BAY-1816032, Biochemical
Full Product Name
BAY-1816032
Product Gene Name
BAY-1816032 biochemical
Product Synonym Names
BAY1816032; 2-(3, 5-difluoro-4-((3-(5-methoxy-4-((3-methoxypyridin-4-yl)amino)pyrimidin-2-yl)-1H-indazol-1-yl)methyl)phenoxy)ethan-1-ol
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Specificity
A potent BUB1 kinase inhibtor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
534.52
Solubilities
>20mg/ml DMSO
Molecular Formula
C??H??F?N?O?
InChi
InChI=1S/C27H24F2N6O4/c1-37-23-13-30-8-7-21(23)32-26-24(38-2)14-31-27(33-26)25-17-5-3-4-6-22(17)35(34-25)15-18-19(28)11-16(12-20(18)29)39-10-9-36/h3-8; 11-14; 36H; 9-10; 15H2; 1-2H3; (H; 30; 31; 32; 33)
InChi Key
QVOGVAVHOLLLAZ-UHFFFAOYSA-N
SMILES
COC1=CN=C(N=C1NC2=C(C=NC=C2)OC)C3=NN(C4=CC=CC=C43)CC5=C(C=C(C=C5F)OCCO)F
CAS Number
1891087-61-8
PubChem CID
118958833

Product Categories/Family for BAY-1816032 biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Other Protein Kinase Inhibitors

Structure of BAY-1816032 biochemical

BAY-1816032 Biochemical – Cat# MBS8400390

Product References and Citations for BAY-1816032 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/118958833

Other Notes

Small volumes of BAY-1816032 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY-1816032 purchase

MBS8400390 is a biochemical targeting BAY-1816032.
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