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PF-04929113

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400402

PF-04929113 is a prodrug for the Hsp90 inhibitor, PF-04958473 (SNX-2112). It binds both Hsp90alpha and Hsp90beta with an IC50 value of 30nM. PF-04929113, is rapidly absorbed and converted into the active inhibitor after oral administration. The active… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-04929113, Biochemical
Full Product Name
PF-04929113
Product Gene Name
PF-04929113 biochemical
Product Synonym Names
PF04929113, glycine, trans-4-[[2-(aminocarbonyl)-5-[4, 5, 6, 7-tetrahydro-6, 6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]phenyl]amino]cyclohexyl ester
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Specificity
A prodrug for the Hsp90 inhibitor; PF-04958473 (SNX-2112)
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
521.53
Solubilities
>50mg/ml DMSO
Molecular Formula
C??H??F?N?O?
InChi
InChI=1S/C25H30F3N5O4/c1-24(2)10-18-21(19(34)11-24)22(25(26; 27)28)32-33(18)14-5-8-16(23(30)36)17(9-14)31-13-3-6-15(7-4-13)37-20(35)12-29/h5; 8-9; 13; 15; 31H; 3-4; 6-7; 10-12; 29H2; 1-2H3; (H2; 30; 36)
InChi Key
AVDSOVJPJZVBTC-UHFFFAOYSA-N
SMILES
CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)OC(=O)CN)C(F)(F)F)C
CAS Number
908115-27-5
PubChem CID
44195571

Product Categories/Family for PF-04929113 biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Heat Shock Protein (Hsp) Inhibitors; Enzyme Inhibitors; Enzyme Inhibitors (A-Z)

Structure of PF-04929113 biochemical

PF-04929113 Biochemical – Cat# MBS8400402

Product References and Citations for PF-04929113 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/44195571

Other Notes

Small volumes of PF-04929113 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-04929113 purchase

MBS8400402 is a biochemical targeting PF-04929113.
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