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CVT-10216

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400404

CVT-10216 is a potent, selective, and reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300nM for ALDH2 and ALDH1, respectively). CVT-10216 has been reported to reduce excessive alcohol drinking in alcohol-preferring rats and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CVT-10216, Biochemical
Full Product Name
CVT-10216
Product Gene Name
CVT-10216 biochemical
Product Synonym Names
3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]benzoic acid, CVT10216, GS-455534
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Specificity
A potent and selective ALDH2 inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
465.48
Solubilities
>40mg/ml DMSO
Molecular Formula
C??H??NO?S
InChi
InChI=1S/C24H19NO7S/c1-33(29; 30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12; 14; 25H; 13H2; 1H3; (H; 27; 28)
InChi Key
YYOOFJZTRCPVFD-UHFFFAOYSA-N
SMILES
CS(=O)(=O)NC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)OCC4=CC(=CC=C4)C(=O)O
CAS Number
1005334-57-5
PubChem CID
23661666

Product Categories/Family for CVT-10216 biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of CVT-10216 biochemical

CVT-10216 Biochemical – Cat# MBS8400404

Product References and Citations for CVT-10216 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/23661666

Other Notes

Small volumes of CVT-10216 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CVT-10216 purchase

MBS8400404 is a biochemical targeting CVT-10216.
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