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(Z)-Guggulsterone

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400412

(Z)-Guggulsterone is a synthetic form of the guggul tree plant steroid that displays an ability to lower LDL cholesterol and triglyceride levels. Acts as a selective antagonist of farnesoid X receptor (FXR) and inhibits FXR transactivation (IC50 = 10uM in the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
(Z)-Guggulsterone, Biochemical
Full Product Name
(Z)-Guggulsterone
Product Synonym Names
4, 17(20)-trans-Pregnadiene-3, 16-dione, (17Z)-Pregna-4, 17(20)-diene-3, 16-dione
Form/Format
Off-white solid
Purity/Purification
>=98%
Specificity
A selective farnesoid X receptor (FXR) modulator
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36months
Country of Origin: USA
Molecular Weight
312.45
Solubilities
>5mg/ml DMSO
Molecular Formula
C??H??O?
InChi
InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13; 2)17(15)8-10-21(16; 18)3/h4; 11; 15; 17-18H; 5-10; 12H2; 1-3H3/b16-4+/t15-; 17+; 18+; 20+; 21-/m1/s1
InChi Key
WDXRGPWQVHZTQJ-OSJVMJFVSA-N
SMILES
CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
CAS Number
39025-23-5
MDL Number
MFCD01310757
PubChem CID
6450278

Product Categories/Family for (Z)-Guggulsterone biochemical

Web Categories; Biochemicals; Biochemicals (A-Z); Activators-Inducers; Agonists; Other Agonists

Structure of (Z)-Guggulsterone biochemical

(Z)-Guggulsterone Biochemical – Cat# MBS8400412

Product References and Citations for (Z)-Guggulsterone biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/6450278

Other Notes

Small volumes of (Z)-Guggulsterone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (Z)-Guggulsterone purchase

MBS8400412 is a biochemical targeting (Z)-Guggulsterone.
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