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Montelukast sodium

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400417

Montelukast is a brain-penetrant cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 4.9nM in HEK293 cell membranes expressing the human receptor). It is selective for CysLT1 over CysLT2 receptors (IC50 = >10, 000nM in COS-7 cell membranes expressing… More details

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Product Overview

Product Name
Montelukast sodium, Biochemical
Full Product Name
Montelukast sodium
Product Synonym Names
MK-476, 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt
Form/Format
White solid
Purity/Purification
>=98%
Specificity
A CysLT1 and GPR17 antagonist
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
608.2
Solubilities
~30mg/ml DMSO; ~10mg/ml Water
Molecular Formula
C??H??ClNO?S-Na
InChi
InChI=1S/C35H36ClNO3S.Na/c1-34(2; 40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12; 14-16; 20-21; 32; 40H; 13; 17-19; 22-23H2; 1-2H3; (H; 38; 39);/q;+1/p-1/b15-10+;/t32-;/m1./s1
InChi Key
LBFBRXGCXUHRJY-HKHDRNBDSA-M
SMILES
CC(C)(O)C(C=CC=C1)=C1CC[C@@H](SCC2(CC2)CC([O-])=O)C3=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=CC=C3.[Na+]
CAS Number
151767-02-1
MDL Number
MFCD00931431
PubChem CID
23663996

Product Categories/Family for Montelukast sodium biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Other Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z)

Structure of Montelukast sodium biochemical

Montelukast Sodium Biochemical – Cat# MBS8400417

Product References and Citations for Montelukast sodium biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/23663996

Other Notes

Small volumes of Montelukast sodium biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Montelukast sodium purchase

MBS8400417 is a biochemical targeting Montelukast sodium.
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