Aldolase C (ALDOC) Antibody – Mouse Monoclonal

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lyase; EC 4.1.2.13

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; mitochondrion; axon; cytosol

Molecular Function: protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity

Biological Process: organ regeneration; glycolysis; apoptosis; glucose metabolic process; pathogenesis; response to organic nitrogen; response to organic cyclic substance; gluconeogenesis; protein homotetramerization; fructose 1,6-bisphosphate metabolic process; epithelial cell differentiation; carbohydrate metabolic process; response to hypoxia; protein heterotetramerization; fructose metabolic process; aging