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Adaphostin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400425

Adaphostin is a p210bcr/abl tyrosine kinase inhibitor (IC50 = 14uM) that displays anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Adaphostin, Biochemical
Full Product Name
Adaphostin
Product Synonym Names
AG 957 Adamantyl Ester; NSC-680410; 4-[[(2, 5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13, 7]dec-1-yl ester
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Specificity
A p210bcr/abl kinase inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
393.48
Solubilities
>30mg/ml Ethanol; >30mg/ml DMSO
Molecular Formula
C??H??NO?
InChi
InChI=1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6; 10; 15-17; 25-27H; 7-9; 11-14H2
InChi Key
YJZSUCFGHXQWDM-UHFFFAOYSA-N
SMILES
C1C2CC3CC1CC(C2)(C3)OC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
CAS Number
241127-58-2
MDL Number
MFCD06411386
PubChem CID
387042

Product Categories/Family for Adaphostin biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Other Protein Kinase Inhibitors

Structure of Adaphostin biochemical

Adaphostin Biochemical – Cat# MBS8400425

Product References and Citations for Adaphostin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/387042

Other Notes

Small volumes of Adaphostin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adaphostin purchase

MBS8400425 is a biochemical targeting Adaphostin.
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