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PCI-29732

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400426

PCI-29732 is a selective and irreversible BTK (Bruton's tyrosine kinase) inhibitor with IC50 of 8.2nM in a FRET based biochemical enzymology assay. Blocks B cell antigen receptor (BCR)-mediated gene expression in CD20+ B cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PCI-29732, Biochemical
Full Product Name
PCI-29732
Product Synonym Names
1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3, 4-d]pyrimidin-4-amine
Form/Format
Beige solid
Purity/Purification
>=98% by HPLC
Specificity
A potent BTK inhibitor
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
371.44
Solubilities
>30mg/ml DMSO
Molecular Formula
C??H??N?O
InChi
InChI=1S/C22H21N5O/c23-21-19-20(26-27(16-6-4-5-7-16)22(19)25-14-24-21)15-10-12-18(13-11-15)28-17-8-2-1-3-9-17/h1-3; 8-14; 16H; 4-7H2; (H2; 23; 24; 25)
InChi Key
GMJUPMONHWAZCP-UHFFFAOYSA-N
SMILES
C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
CAS Number
330786-25-9
PubChem CID
22347110

Product Categories/Family for PCI-29732 biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Protein Kinase Inhibitors; Bruton's Tyrosine Kinase (BTK) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Signal Transduction; Protein Ki

Structure of PCI-29732 biochemical

PCI-29732 Biochemical – Cat# MBS8400426

Product References and Citations for PCI-29732 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/22347110

Other Notes

Small volumes of PCI-29732 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCI-29732 purchase

MBS8400426 is a biochemical targeting PCI-29732.
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